Exosome mediated delivery of Epigallocatechin 3 gallate as a novel approach to alleviate psoriasis symptoms through cytokine and apoptotic pathway modulation.

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Title: Exosome mediated delivery of Epigallocatechin 3 gallate as a novel approach to alleviate psoriasis symptoms through cytokine and apoptotic pathway modulation.
Authors: Kishta MS; Hormones department, Medical Research and clinical studies institute, National Research Centre, Dokki, Cairo, 12622, Egypt. kishtamsa@gmail.com.; Stem Cell Lab, Center of Excellence for Advanced Sciences, National Research Centre, Dokki, Cairo, 12622, Egypt. kishtamsa@gmail.com.; Researcher of Biotechnology, Hormones Department, Medical Research and Clinical Studies Institute, National Research Centre, Giza, 12622, Egypt. kishtamsa@gmail.com., Abd-Rabou AA; Hormones department, Medical Research and clinical studies institute, National Research Centre, Dokki, Cairo, 12622, Egypt.; Stem Cell Lab, Center of Excellence for Advanced Sciences, National Research Centre, Dokki, Cairo, 12622, Egypt., Sarkissian GK; Biotechnology Faculty, October University for Modern Sciences and Arts (MSA), 6th of October City, Giza, 12451, Egypt., Elwakil AI; Biotechnology Faculty, October University for Modern Sciences and Arts (MSA), 6th of October City, Giza, 12451, Egypt., Elsabry DM; Biotechnology Faculty, October University for Modern Sciences and Arts (MSA), 6th of October City, Giza, 12451, Egypt., Zagzoug YM; Biotechnology Faculty, October University for Modern Sciences and Arts (MSA), 6th of October City, Giza, 12451, Egypt., Hussein SR; Biotechnology Faculty, October University for Modern Sciences and Arts (MSA), 6th of October City, Giza, 12451, Egypt., Abdallah AN; Hormones department, Medical Research and clinical studies institute, National Research Centre, Dokki, Cairo, 12622, Egypt. an.noureldine@nrc.sci.eg.; Stem Cell Lab, Center of Excellence for Advanced Sciences, National Research Centre, Dokki, Cairo, 12622, Egypt. an.noureldine@nrc.sci.eg.
Source: Scientific reports [Sci Rep] 2025 Aug 16; Vol. 15 (1), pp. 30013. Date of Electronic Publication: 2025 Aug 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-025-10886-2