Bioinspired ruthenium-manganese-oxygen complex for biocatalytic and radiosensitization therapies to eradicate primary and metastatic tumors.

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Title: Bioinspired ruthenium-manganese-oxygen complex for biocatalytic and radiosensitization therapies to eradicate primary and metastatic tumors.
Authors: Li R; Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, China., Wang T; College of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu, China., Mu S; College of Biological Engineering, Sichuan University of Science and Engineering, Yibin, China., Xing Z; College of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu, China., Ding Z; College of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu, China., Wen Q; Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, China., Wei Z; Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, China., Wang X; School of Pharmacy and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macao, China., Adeli M; Institute of Chemistry and Biochemistry, Free University of Berlin, Berlin, Germany., Li S; College of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu, China., Cheng C; College of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu, China. chong.cheng@scu.edu.cn.; Department of Endodontics, State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. chong.cheng@scu.edu.cn., Peng X; Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, China. pxx2014@scu.edu.cn.
Source: Nature communications [Nat Commun] 2025 Aug 16; Vol. 16 (1), pp. 7640. Date of Electronic Publication: 2025 Aug 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-62999-x