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Inhibiting the alarmin-driven hematopoiesis-stromal cell crosstalk in primary myelofibrosis ameliorates bone marrow fibrosis.

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Title: Inhibiting the alarmin-driven hematopoiesis-stromal cell crosstalk in primary myelofibrosis ameliorates bone marrow fibrosis.
Authors: Gleitz HFE; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.; Department of Cell and Tumor Biology, Faculty of Medicine University Hospital RWTH Aachen Aachen Germany., Fuchs SNR; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands., Snoeren IAM; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands., Boys C; Institute for Computational Biomedicine, Faculty of Medicine, and Heidelberg University Hospital Heidelberg University Heidelberg Germany., Nagai J; Institute for Computational Genomics, Faculty of Medicine RWTH Aachen University Aachen Germany., Tejeda-Mora H; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands., Klöker V; Institute for Computational Genomics, Faculty of Medicine RWTH Aachen University Aachen Germany., Pritchard JE; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.; Department of Cell and Tumor Biology, Faculty of Medicine University Hospital RWTH Aachen Aachen Germany., Bakker IJ; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands., Gargallo Garasa M; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands., Bindels E; Department of Hematology Erasmus Medical Center Cancer Institute Rotterdam The Netherlands., Saez-Rodriguez J; Institute for Computational Biomedicine, Faculty of Medicine, and Heidelberg University Hospital Heidelberg University Heidelberg Germany., Vogl T; Institute of Immunology University of Münster Münster Germany., Kramann R; Institute of Experimental Medicine and Systems Biology, Medical Faculty RWTH Aachen University Aachen Germany.; Division of Nephrology and Clinical Immunology, Medical Faculty RWTH Aachen University Aachen Germany.; Department of Internal Medicine, Nephrology and Transplantation Erasmus Medical Center Rotterdam The Netherlands., Dugourd A; Institute for Computational Biomedicine, Faculty of Medicine, and Heidelberg University Hospital Heidelberg University Heidelberg Germany., Costa IG; Institute for Computational Genomics, Faculty of Medicine RWTH Aachen University Aachen Germany., Schneider RK; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.; Department of Cell and Tumor Biology, Faculty of Medicine University Hospital RWTH Aachen Aachen Germany.
Source: HemaSphere [Hemasphere] 2025 Aug 14; Vol. 9 (8), pp. e70179. Date of Electronic Publication: 2025 Aug 14 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibiting the alarmin-driven hematopoiesis-stromal cell crosstalk in primary myelofibrosis ameliorates bone marrow fibrosis.
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  Data: <searchLink fieldCode="AU" term="%22Gleitz+HFE%22">Gleitz HFE</searchLink>; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.; Department of Cell and Tumor Biology, Faculty of Medicine University Hospital RWTH Aachen Aachen Germany.<br /><searchLink fieldCode="AU" term="%22Fuchs+SNR%22">Fuchs SNR</searchLink>; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Snoeren+IAM%22">Snoeren IAM</searchLink>; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Boys+C%22">Boys C</searchLink>; Institute for Computational Biomedicine, Faculty of Medicine, and Heidelberg University Hospital Heidelberg University Heidelberg Germany.<br /><searchLink fieldCode="AU" term="%22Nagai+J%22">Nagai J</searchLink>; Institute for Computational Genomics, Faculty of Medicine RWTH Aachen University Aachen Germany.<br /><searchLink fieldCode="AU" term="%22Tejeda-Mora+H%22">Tejeda-Mora H</searchLink>; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Klöker+V%22">Klöker V</searchLink>; Institute for Computational Genomics, Faculty of Medicine RWTH Aachen University Aachen Germany.<br /><searchLink fieldCode="AU" term="%22Pritchard+JE%22">Pritchard JE</searchLink>; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.; Department of Cell and Tumor Biology, Faculty of Medicine University Hospital RWTH Aachen Aachen Germany.<br /><searchLink fieldCode="AU" term="%22Bakker+IJ%22">Bakker IJ</searchLink>; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gargallo+Garasa+M%22">Gargallo Garasa M</searchLink>; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bindels+E%22">Bindels E</searchLink>; Department of Hematology Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Saez-Rodriguez+J%22">Saez-Rodriguez J</searchLink>; Institute for Computational Biomedicine, Faculty of Medicine, and Heidelberg University Hospital Heidelberg University Heidelberg Germany.<br /><searchLink fieldCode="AU" term="%22Vogl+T%22">Vogl T</searchLink>; Institute of Immunology University of Münster Münster Germany.<br /><searchLink fieldCode="AU" term="%22Kramann+R%22">Kramann R</searchLink>; Institute of Experimental Medicine and Systems Biology, Medical Faculty RWTH Aachen University Aachen Germany.; Division of Nephrology and Clinical Immunology, Medical Faculty RWTH Aachen University Aachen Germany.; Department of Internal Medicine, Nephrology and Transplantation Erasmus Medical Center Rotterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dugourd+A%22">Dugourd A</searchLink>; Institute for Computational Biomedicine, Faculty of Medicine, and Heidelberg University Hospital Heidelberg University Heidelberg Germany.<br /><searchLink fieldCode="AU" term="%22Costa+IG%22">Costa IG</searchLink>; Institute for Computational Genomics, Faculty of Medicine RWTH Aachen University Aachen Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+RK%22">Schneider RK</searchLink>; Department of Developmental Biology Erasmus Medical Center Rotterdam The Netherlands.; Oncode Institute Erasmus Medical Center Cancer Institute Rotterdam The Netherlands.; Department of Cell and Tumor Biology, Faculty of Medicine University Hospital RWTH Aachen Aachen Germany.
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  Data: <searchLink fieldCode="JN" term="%22101740619%22">HemaSphere</searchLink> [Hemasphere] 2025 Aug 14; Vol. 9 (8), pp. e70179. <i>Date of Electronic Publication: </i>2025 Aug 14 (<i>Print Publication: </i>2025).
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