Shenyuan granules improve cellular senescence through Klotho-mediated p16/p21 signaling pathway in diabetic kidney disease.

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Title: Shenyuan granules improve cellular senescence through Klotho-mediated p16/p21 signaling pathway in diabetic kidney disease.
Authors: Guo X; School of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, China., Zhang S; School of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, China., Sun Q; School of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, China., Li H; School of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, China., Wang L; The First Clinical College, Hubei University of Chinese Medicine, Wuhan, China.; Hubei Provincial Hospital of Traditional Chinese Medicine, Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China.; Hubei Shizhen Laboratory, Wuhan, China.; Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in Traditional Chinese Medicine, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.
Source: Frontiers in medicine [Front Med (Lausanne)] 2025 Jul 31; Vol. 12, pp. 1627412. Date of Electronic Publication: 2025 Jul 31 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101648047 Publication Model: eCollection Cited Medium: Print ISSN: 2296-858X (Print) Linking ISSN: 2296858X NLM ISO Abbreviation: Front Med (Lausanne) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2296-858X
DOI:10.3389/fmed.2025.1627412