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Increased longevity of circulating human IgG in an NSG Fc gamma receptor-1 deficient humanized mouse model.

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Title: Increased longevity of circulating human IgG in an NSG Fc gamma receptor-1 deficient humanized mouse model.
Authors: Megathlin HR; The Jackson Laboratory, Bar Harbor, Maine 04609, USA; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME 04469, USA., Burzenski L; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., Brehm MA; Program in Molecular Medicine, Diabetes Center of Excellence, UMass Chan Medical School, Worcester, MA 01605, USA., Greiner DL; Program in Molecular Medicine, Diabetes Center of Excellence, UMass Chan Medical School, Worcester, MA 01605, USA., Balu-Iyer S; Department of Pharmaceutical Sciences, University of Buffalo, The State University of New York, Buffalo, NY 14261, USA., Shultz LD; The Jackson Laboratory, Bar Harbor, Maine 04609, USA; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME 04469, USA. Electronic address: lenny.shultz@jax.org.
Source: Journal of pharmaceutical sciences [J Pharm Sci] 2025 Oct; Vol. 114 (10), pp. 103964. Date of Electronic Publication: 2025 Aug 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Increased longevity of circulating human IgG in an NSG Fc gamma receptor-1 deficient humanized mouse model.
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  Data: <searchLink fieldCode="AU" term="%22Megathlin+HR%22">Megathlin HR</searchLink>; The Jackson Laboratory, Bar Harbor, Maine 04609, USA; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME 04469, USA.<br /><searchLink fieldCode="AU" term="%22Burzenski+L%22">Burzenski L</searchLink>; The Jackson Laboratory, Bar Harbor, Maine 04609, USA.<br /><searchLink fieldCode="AU" term="%22Brehm+MA%22">Brehm MA</searchLink>; Program in Molecular Medicine, Diabetes Center of Excellence, UMass Chan Medical School, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Greiner+DL%22">Greiner DL</searchLink>; Program in Molecular Medicine, Diabetes Center of Excellence, UMass Chan Medical School, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Balu-Iyer+S%22">Balu-Iyer S</searchLink>; Department of Pharmaceutical Sciences, University of Buffalo, The State University of New York, Buffalo, NY 14261, USA.<br /><searchLink fieldCode="AU" term="%22Shultz+LD%22">Shultz LD</searchLink>; The Jackson Laboratory, Bar Harbor, Maine 04609, USA; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME 04469, USA. Electronic address: lenny.shultz@jax.org.
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  Data: <searchLink fieldCode="JN" term="%222985195R%22">Journal of pharmaceutical sciences</searchLink> [J Pharm Sci] 2025 Oct; Vol. 114 (10), pp. 103964. <i>Date of Electronic Publication: </i>2025 Aug 16.
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