Antiferroptotic Drugs Reduce sFlt-1 Release and Placenta Damage in Preeclampsia.

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Title: Antiferroptotic Drugs Reduce sFlt-1 Release and Placenta Damage in Preeclampsia.
Authors: Lianski S; Obstetrics and Gynecology Division, Hadassah Medical Center, Faculty of Medicine of the Hebrew University of Jerusalem, Israel (S.L., T.M., L.T.-M., S.E.-G., S.Y., D.G.-W., S.M.C., O. Beharier)., Mizrachi T; Obstetrics and Gynecology Division, Hadassah Medical Center, Faculty of Medicine of the Hebrew University of Jerusalem, Israel (S.L., T.M., L.T.-M., S.E.-G., S.Y., D.G.-W., S.M.C., O. Beharier)., Barak O; Magee-Womens Research Institute, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh (O. Barak, Y.S.).; Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Israel (O. Barak)., Tsaitlin-Mor L; Obstetrics and Gynecology Division, Hadassah Medical Center, Faculty of Medicine of the Hebrew University of Jerusalem, Israel (S.L., T.M., L.T.-M., S.E.-G., S.Y., D.G.-W., S.M.C., O. Beharier)., Elhaik-Goldman S; Obstetrics and Gynecology Division, Hadassah Medical Center, Faculty of Medicine of the Hebrew University of Jerusalem, Israel (S.L., T.M., L.T.-M., S.E.-G., S.Y., D.G.-W., S.M.C., O. Beharier)., Yagel S; Obstetrics and Gynecology Division, Hadassah Medical Center, Faculty of Medicine of the Hebrew University of Jerusalem, Israel (S.L., T.M., L.T.-M., S.E.-G., S.Y., D.G.-W., S.M.C., O. Beharier)., Goldman-Wohl D; Obstetrics and Gynecology Division, Hadassah Medical Center, Faculty of Medicine of the Hebrew University of Jerusalem, Israel (S.L., T.M., L.T.-M., S.E.-G., S.Y., D.G.-W., S.M.C., O. Beharier)., Cohen SM; Obstetrics and Gynecology Division, Hadassah Medical Center, Faculty of Medicine of the Hebrew University of Jerusalem, Israel (S.L., T.M., L.T.-M., S.E.-G., S.Y., D.G.-W., S.M.C., O. Beharier)., Hefetz Medina R; Goldyne Savad Institute of Gene Therapy, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Israel (R.H.M., J.R.)., Rachmilewitz J; Goldyne Savad Institute of Gene Therapy, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Israel (R.H.M., J.R.)., Barr HM; The Wohl Drug Discovery Institute of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel (H.M.B., A.P.)., Plotnikov A; The Wohl Drug Discovery Institute of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel (H.M.B., A.P.)., Tyurina YY; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh (Y.Y.T., V.A.T., A.A.K., V.E.K.)., Tyurin VA; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh (Y.Y.T., V.A.T., A.A.K., V.E.K.)., Samovich SN; Department of Pediatrics, Division of Critical Care and Hospital Medicine, Redox Health Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY (S.N.S., V.E.K., H.B.)., Kapralov AA; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh (Y.Y.T., V.A.T., A.A.K., V.E.K.)., Karumanchi SA; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA (S.A.K.)., Kagan VE; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh (Y.Y.T., V.A.T., A.A.K., V.E.K.).; Department of Pediatrics, Division of Critical Care and Hospital Medicine, Redox Health Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY (S.N.S., V.E.K., H.B.)., Bayir H; Department of Pediatrics, Division of Critical Care and Hospital Medicine, Redox Health Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY (S.N.S., V.E.K., H.B.)., Sadovsky Y; Magee-Womens Research Institute, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh (O. Barak, Y.S.)., Beharier O; Obstetrics and Gynecology Division, Hadassah Medical Center, Faculty of Medicine of the Hebrew University of Jerusalem, Israel (S.L., T.M., L.T.-M., S.E.-G., S.Y., D.G.-W., S.M.C., O. Beharier).
Source: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2025 Oct; Vol. 82 (10), pp. 1705-1718. Date of Electronic Publication: 2025 Aug 19.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 7906255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4563 (Electronic) Linking ISSN: 0194911X NLM ISO Abbreviation: Hypertension Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1524-4563
DOI:10.1161/HYPERTENSIONAHA.125.25003