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Successful off-label use of elexacaftor/tezacaftor/ivacaftor in an infant with severe CF disease.

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Title: Successful off-label use of elexacaftor/tezacaftor/ivacaftor in an infant with severe CF disease.
Authors: Shevill E; Department of Respiratory Medicine, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia., Wainwright CE; Department of Respiratory Medicine, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia; Child Health Research Centre, University of Queensland, Queensland, Australia., Churchett M; Department of Dietetics, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia., Sexton J; Department of Physiotherapy, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia., Irving H; Centre for Children's Health Ethics and Law, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia., Manoy S; Centre for Children's Health Ethics and Law, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia., Figgins S; Department of Pharmacy, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia., Swyer K; Department of Social Work, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia., Fazackerley LA; School of Exercise and Nutrition Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia., Robinson PD; Department of Respiratory Medicine, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia; Child Health Research Centre, University of Queensland, Queensland, Australia. Electronic address: paul.robinson@uq.edu.au.
Source: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2025 Sep; Vol. 24 (5), pp. 935-938. Date of Electronic Publication: 2025 Aug 18.
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5010 (Electronic) Linking ISSN: 15691993 NLM ISO Abbreviation: J Cyst Fibros Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Successful off-label use of elexacaftor/tezacaftor/ivacaftor in an infant with severe CF disease.
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  Data: <searchLink fieldCode="AU" term="%22Shevill+E%22">Shevill E</searchLink>; Department of Respiratory Medicine, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Wainwright+CE%22">Wainwright CE</searchLink>; Department of Respiratory Medicine, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia; Child Health Research Centre, University of Queensland, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Churchett+M%22">Churchett M</searchLink>; Department of Dietetics, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Sexton+J%22">Sexton J</searchLink>; Department of Physiotherapy, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Irving+H%22">Irving H</searchLink>; Centre for Children's Health Ethics and Law, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Manoy+S%22">Manoy S</searchLink>; Centre for Children's Health Ethics and Law, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Figgins+S%22">Figgins S</searchLink>; Department of Pharmacy, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Swyer+K%22">Swyer K</searchLink>; Department of Social Work, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Fazackerley+LA%22">Fazackerley LA</searchLink>; School of Exercise and Nutrition Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Robinson+PD%22">Robinson PD</searchLink>; Department of Respiratory Medicine, Queensland Children's Hospital (QCH), Brisbane, Queensland, Australia; Child Health Research Centre, University of Queensland, Queensland, Australia. Electronic address: paul.robinson@uq.edu.au.
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  Data: <searchLink fieldCode="JN" term="%22101128966%22">Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society</searchLink> [J Cyst Fibros] 2025 Sep; Vol. 24 (5), pp. 935-938. <i>Date of Electronic Publication: </i>2025 Aug 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101128966 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-5010 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215691993%22">15691993 </searchLink><i>NLM ISO Abbreviation: </i>J Cyst Fibros <i>Subsets: </i>MEDLINE; In Process
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40829988
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        Value: 10.1016/j.jcf.2025.08.006
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        Text: English
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              Text: 2025 Sep
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