Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids.
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| Title: | Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids. |
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| Authors: | Yeisley DJ; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA., Ren L; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA., Papineau KS; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA., Schnackenberg LK; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA., Gamboa da Costa G; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA., Patterson TA; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA., Fitzpatrick SC; U.S. Food and Drug Administration, Human Foods Program, College Park, MD, USA., Shi Q; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA. |
| Source: | Biochemistry and biophysics reports [Biochem Biophys Rep] 2025 Aug 11; Vol. 43, pp. 102199. Date of Electronic Publication: 2025 Aug 11 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101660999 Publication Model: eCollection Cited Medium: Internet ISSN: 2405-5808 (Electronic) Linking ISSN: 24055808 NLM ISO Abbreviation: Biochem Biophys Rep Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40832469 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Yeisley+DJ%22">Yeisley DJ</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Ren+L%22">Ren L</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Papineau+KS%22">Papineau KS</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Schnackenberg+LK%22">Schnackenberg LK</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Gamboa+da+Costa+G%22">Gamboa da Costa G</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Patterson+TA%22">Patterson TA</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Fitzpatrick+SC%22">Fitzpatrick SC</searchLink>; U.S. Food and Drug Administration, Human Foods Program, College Park, MD, USA.<br /><searchLink fieldCode="AU" term="%22Shi+Q%22">Shi Q</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research (NCTR), Jefferson, AR, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101660999%22">Biochemistry and biophysics reports</searchLink> [Biochem Biophys Rep] 2025 Aug 11; Vol. 43, pp. 102199. <i>Date of Electronic Publication: </i>2025 Aug 11 (<i>Print Publication: </i>2025). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101660999 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2405-5808 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224055808%22">24055808 </searchLink><i>NLM ISO Abbreviation: </i>Biochem Biophys Rep <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40832469 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bbrep.2025.102199 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 102199 Titles: – TitleFull: Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yeisley DJ – PersonEntity: Name: NameFull: Ren L – PersonEntity: Name: NameFull: Papineau KS – PersonEntity: Name: NameFull: Schnackenberg LK – PersonEntity: Name: NameFull: Gamboa da Costa G – PersonEntity: Name: NameFull: Patterson TA – PersonEntity: Name: NameFull: Fitzpatrick SC – PersonEntity: Name: NameFull: Shi Q IsPartOfRelationships: – BibEntity: Dates: – D: 11 M: 08 Text: 2025 Aug 11 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2405-5808 Numbering: – Type: volume Value: 43 Titles: – TitleFull: Biochemistry and biophysics reports Type: main |
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