Is 2nd JAKi treatment for UC worth the effort? A retrospective, multi-centre UK study.

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Title: Is 2nd JAKi treatment for UC worth the effort? A retrospective, multi-centre UK study.
Authors: Radia C; Department of Gastroenterology, King's College Hospital NHS Foundation Trust, London, SE5 9RS, United Kingdom.; School of Immunology and Microbial Sciences, King's College London Faculty of Life Sciences & Medicine, London, WC2R 2LS, United Kingdom., Danso Y; Gastroenterology, Barts Health NHS Trust, London, E1 1BB, United Kingdom., Ritchie S; Gastroenterology, County Durham and Darlington NHS Foundation Trust, Darlington, DL3 6HX, United Kingdom., Hale M; Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, S10 2JF, United Kingdom., Elford AT; Edinburgh IBD Unit, Western General Hospital, Edinburgh, EH4 2XU, United Kingdom.; Medicine, The University of Melbourne, Melbourne, VIC, 3010, Australia., Patel C; Gastroenterology, Guy's and St Thomas' Hospitals NHS Trust, London, SE1 7EH, United Kingdom., Hicks L; Gastroenterology, Imperial College Healthcare NHS Trust, London, W2 1NY, United Kingdom., Kalyanji S; Gastroenterology, St George's University Hospitals NHS Foundation Trust, London, SW17 0QT, United Kingdom., Dong C; Gastroenterology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, NE1 4LP, United Kingdom., Yeung K; Gastroenterology, St Mark's Hospital and Academic Institute, London, HA1 3UJ, United Kingdom., Yeo JH; Gastroenterology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, United Kingdom., Allah-Ditta M; Gastroenterology, Calderdale and Huddersfield NHS Foundation Trust, Huddersfield, HX3 0PW, United Kingdom., Bishara M; Gastroenterology, Royal Devon University Healthcare NHS Foundation Trust, Exeter, EX2 5DW, United Kingdom., Sethi-Arora K; Gastroenterology, Northern Care Alliance NHS Foundation Trust, Salford, Manchester, M6 8HD, United Kingdom., Pillay L; Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, United Kingdom., Johnston EL; Gastroenterology, West Middlesex University Hospital, Isleworth, TW7 6AF, United Kingdom., Rudling R; Gastroenterology, Mid Yorkshire Hospitals NHS Trust, Wakefield, WF1 4DG, United Kingdom., Rees F; Gastroenterology, University Hospitals Sussex NHS Foundation Trust, Worthing, BN2 5BE, United Kingdom., Harvey P; Department of Gastroenterology, Royal Wolverhampton Hospitals NHS Trust, Heath Town, Wolverhampton, WV10 0QP, United Kingdom., Trodden-Mittnacht H; Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, LS1 3EX, United Kingdom., Davis E; Gastroenterology, Oxford University Hospitals NHS Foundation Trust, Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom., Fraser A; Gastroenterology, University Hospitals Bristol NHS Foundation Trust, Bristol, BS2 8HW, United Kingdom.; Gastroenterology, Weston Area Health NHS Trust, Bristol, BS23 4TQ, United Kingdom., Sawan NJ; Queen Elizabeth Woolwich, London, SE18 4QH, United Kingdom., Hussain MA; Gastroenterology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2GW, United Kingdom., Campbell R; Gastroenterology, Queen Elizabeth University Hospital, Glasgow, G51 4TF, United Kingdom., George B; Department of Gastroenterology, Torbay and South Devon NHS Foundation Trust, Torquay, Torbay, TQ2 7AA, United Kingdom., Rawcliffe M; Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, S10 2JF, United Kingdom., Choon XY; Gastroenterology, Guy's and St Thomas' Hospitals NHS Trust, London, SE1 7EH, United Kingdom., Shah K; Gastroenterology, Barts Health NHS Trust, London, E1 1BB, United Kingdom., Al-Zarrad D; Gastroenterology, St Mark's Hospital and Academic Institute, London, HA1 3UJ, United Kingdom., Toft J; Gastroenterology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, United Kingdom., Chhabra P; Gastroenterology, Calderdale and Huddersfield NHS Foundation Trust, Huddersfield, HX3 0PW, United Kingdom., Burr N; Gastroenterology, Mid Yorkshire Hospitals NHS Trust, Wakefield, WF1 4DG, United Kingdom.; Gastroenterology, University Hospitals Sussex NHS Foundation Trust, Worthing, BN2 5BE, United Kingdom., Hewitt A; Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, LS1 3EX, United Kingdom., Kumar R; Gastroenterology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2GW, United Kingdom., McCartney S; Gastroenterology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, United Kingdom., Rosiou K; Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, LS1 3EX, United Kingdom., Dhar A; Gastroenterology, County Durham and Darlington NHS Foundation Trust, Darlington, DL3 6HX, United Kingdom., Lees CW; Edinburgh IBD Unit, Western General Hospital, Edinburgh, EH4 2XU, United Kingdom.; Centre for Genomics and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh Western General Hospital, Edinburgh, EH4 2XU, United Kingdom., Lamb CA; Gastroenterology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, NE1 4LP, United Kingdom.; Translational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE1 7RU, United Kingdom., Speight A; Gastroenterology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, NE1 4LP, United Kingdom., Ahmad T; Gastroenterology, Royal Devon University Healthcare NHS Foundation Trust, Exeter, EX2 5DW, United Kingdom.; Precision Medicine Exeter, University of Exeter, Exeter, EX4 4PY, United Kingdom., Limdi J; Gastroenterology, Northern Care Alliance NHS Foundation Trust, Salford, Manchester, M6 8HD, United Kingdom., Raine T; Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, United Kingdom., Walsh A; Gastroenterology, Oxford University Hospitals NHS Foundation Trust, Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom., Cooney R; Gastroenterology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2GW, United Kingdom., Harrow P; Gastroenterology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, United Kingdom., Patel K; Gastroenterology, St George's University Hospitals NHS Foundation Trust, London, SW17 0QT, United Kingdom., Samaan M; Gastroenterology, Guy's and St Thomas' Hospitals NHS Trust, London, SE1 7EH, United Kingdom., Pavlidis P; Department of Gastroenterology, King's College Hospital NHS Foundation Trust, London, SE5 9RS, United Kingdom., Kent A; Department of Gastroenterology, King's College Hospital NHS Foundation Trust, London, SE5 9RS, United Kingdom., Selinger C; Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, LS1 3EX, United Kingdom.; University of Leeds, Leeds Institute of Biomedical and Clinical Sciences, Leeds, LS2 9JT, United Kingdom., Kok KB; Gastroenterology, Barts Health NHS Trust, London, E1 1BB, United Kingdom.
Source: Journal of Crohn's & colitis [J Crohns Colitis] 2025 Sep 28; Vol. 19 (9).
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101318676 Publication Model: Print Cited Medium: Internet ISSN: 1876-4479 (Electronic) Linking ISSN: 18739946 NLM ISO Abbreviation: J Crohns Colitis Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: <searchLink fieldCode="AU" term="%22Radia+C%22">Radia C</searchLink>; Department of Gastroenterology, King's College Hospital NHS Foundation Trust, London, SE5 9RS, United Kingdom.; School of Immunology and Microbial Sciences, King's College London Faculty of Life Sciences & Medicine, London, WC2R 2LS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Danso+Y%22">Danso Y</searchLink>; Gastroenterology, Barts Health NHS Trust, London, E1 1BB, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ritchie+S%22">Ritchie S</searchLink>; Gastroenterology, County Durham and Darlington NHS Foundation Trust, Darlington, DL3 6HX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hale+M%22">Hale M</searchLink>; Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, S10 2JF, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Elford+AT%22">Elford AT</searchLink>; Edinburgh IBD Unit, Western General Hospital, Edinburgh, EH4 2XU, United Kingdom.; 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Gastroenterology, Mid Yorkshire Hospitals NHS Trust, Wakefield, WF1 4DG, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rees+F%22">Rees F</searchLink>; Gastroenterology, University Hospitals Sussex NHS Foundation Trust, Worthing, BN2 5BE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Harvey+P%22">Harvey P</searchLink>; Department of Gastroenterology, Royal Wolverhampton Hospitals NHS Trust, Heath Town, Wolverhampton, WV10 0QP, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Trodden-Mittnacht+H%22">Trodden-Mittnacht H</searchLink>; Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, LS1 3EX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Davis+E%22">Davis E</searchLink>; Gastroenterology, Oxford University Hospitals NHS Foundation Trust, Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fraser+A%22">Fraser A</searchLink>; Gastroenterology, University Hospitals Bristol NHS Foundation Trust, Bristol, BS2 8HW, United Kingdom.; 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Gastroenterology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, NE1 4LP, United Kingdom.; Translational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE1 7RU, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Speight+A%22">Speight A</searchLink>; Gastroenterology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, NE1 4LP, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ahmad+T%22">Ahmad T</searchLink>; Gastroenterology, Royal Devon University Healthcare NHS Foundation Trust, Exeter, EX2 5DW, United Kingdom.; Precision Medicine Exeter, University of Exeter, Exeter, EX4 4PY, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Limdi+J%22">Limdi J</searchLink>; Gastroenterology, Northern Care Alliance NHS Foundation Trust, Salford, Manchester, M6 8HD, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Raine+T%22">Raine T</searchLink>; Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Walsh+A%22">Walsh A</searchLink>; Gastroenterology, Oxford University Hospitals NHS Foundation Trust, Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cooney+R%22">Cooney R</searchLink>; Gastroenterology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2GW, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Harrow+P%22">Harrow P</searchLink>; Gastroenterology, University College London Hospitals NHS Foundation Trust, London, NW1 2BU, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Patel+K%22">Patel K</searchLink>; Gastroenterology, St George's University Hospitals NHS Foundation Trust, London, SW17 0QT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Samaan+M%22">Samaan M</searchLink>; Gastroenterology, Guy's and St Thomas' Hospitals NHS Trust, London, SE1 7EH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pavlidis+P%22">Pavlidis P</searchLink>; Department of Gastroenterology, King's College Hospital NHS Foundation Trust, London, SE5 9RS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kent+A%22">Kent A</searchLink>; Department of Gastroenterology, King's College Hospital NHS Foundation Trust, London, SE5 9RS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Selinger+C%22">Selinger C</searchLink>; Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, LS1 3EX, United Kingdom.; University of Leeds, Leeds Institute of Biomedical and Clinical Sciences, Leeds, LS2 9JT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kok+KB%22">Kok KB</searchLink>; Gastroenterology, Barts Health NHS Trust, London, E1 1BB, United Kingdom.
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          Dates:
            – D: 28
              M: 09
              Text: 2025 Sep 28
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1876-4479
          Numbering:
            – Type: volume
              Value: 19
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: Journal of Crohn's & colitis
              Type: main
ResultId 1