View in EDS

TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differentiation.

Saved in:
Bibliographic Details
Title: TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differentiation.
Authors: Tuomela K; Department of Surgery, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada., Garcia RV; Department of Surgery, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada., Boardman DA; Department of Surgery, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada., Tavakoli P; Department of Medicine, University of British Columbia, Vancouver, BC, Canada., Ancheta-Schmit M; Department of Medicine, University of British Columbia, Vancouver, BC, Canada., Sham HP; BC Children's Hospital Research Institute, Vancouver, BC, Canada; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Cheng L; Discovery Immunology, Bristol-Myers Squibb, Princeton, NJ, USA., Struthers M; Discovery Immunology, Bristol-Myers Squibb, Princeton, NJ, USA., Bressler B; Department of Medicine, University of British Columbia, Vancouver, BC, Canada., Vallance BA; BC Children's Hospital Research Institute, Vancouver, BC, Canada; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Zhao Q; Discovery Immunology, Bristol-Myers Squibb, Princeton, NJ, USA., Levings MK; Department of Surgery, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada; School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada. Electronic address: mlevings@bcchr.ca.
Source: Cell reports. Medicine [Cell Rep Med] 2025 Sep 16; Vol. 6 (9), pp. 102303. Date of Electronic Publication: 2025 Aug 19.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40834860
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differentiation.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Tuomela+K%22">Tuomela K</searchLink>; Department of Surgery, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Garcia+RV%22">Garcia RV</searchLink>; Department of Surgery, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Boardman+DA%22">Boardman DA</searchLink>; Department of Surgery, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Tavakoli+P%22">Tavakoli P</searchLink>; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Ancheta-Schmit+M%22">Ancheta-Schmit M</searchLink>; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Sham+HP%22">Sham HP</searchLink>; BC Children's Hospital Research Institute, Vancouver, BC, Canada; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Cheng+L%22">Cheng L</searchLink>; Discovery Immunology, Bristol-Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Struthers+M%22">Struthers M</searchLink>; Discovery Immunology, Bristol-Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Bressler+B%22">Bressler B</searchLink>; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Vallance+BA%22">Vallance BA</searchLink>; BC Children's Hospital Research Institute, Vancouver, BC, Canada; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Zhao+Q%22">Zhao Q</searchLink>; Discovery Immunology, Bristol-Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Levings+MK%22">Levings MK</searchLink>; Department of Surgery, University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada; School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada. Electronic address: mlevings@bcchr.ca.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101766894%22">Cell reports. Medicine</searchLink> [Cell Rep Med] 2025 Sep 16; Vol. 6 (9), pp. 102303. <i>Date of Electronic Publication: </i>2025 Aug 19.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101766894 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2666-3791 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226663791%22">26663791 </searchLink><i>NLM ISO Abbreviation: </i>Cell Rep Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40834860
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.xcrm.2025.102303
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 102303
    Titles:
      – TitleFull: TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differentiation.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Tuomela K
      – PersonEntity:
          Name:
            NameFull: Garcia RV
      – PersonEntity:
          Name:
            NameFull: Boardman DA
      – PersonEntity:
          Name:
            NameFull: Tavakoli P
      – PersonEntity:
          Name:
            NameFull: Ancheta-Schmit M
      – PersonEntity:
          Name:
            NameFull: Sham HP
      – PersonEntity:
          Name:
            NameFull: Cheng L
      – PersonEntity:
          Name:
            NameFull: Struthers M
      – PersonEntity:
          Name:
            NameFull: Bressler B
      – PersonEntity:
          Name:
            NameFull: Vallance BA
      – PersonEntity:
          Name:
            NameFull: Zhao Q
      – PersonEntity:
          Name:
            NameFull: Levings MK
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 16
              M: 09
              Text: 2025 Sep 16
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2666-3791
          Numbering:
            – Type: volume
              Value: 6
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: Cell reports. Medicine
              Type: main
ResultId 1