Temporal genomic dynamics shape clinical trajectory in multiple myeloma.
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| Title: | Temporal genomic dynamics shape clinical trajectory in multiple myeloma. |
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| Authors: | Maura F; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA. mauraf@mskcc.org.; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. mauraf@mskcc.org., Kaddoura M; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Poos AM; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg University and German Cancer Research Center (DKFZ), Heidelberg, Germany., Baughn LB; Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Ziccheddu B; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Bärtsch MA; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg University and German Cancer Research Center (DKFZ), Heidelberg, Germany., Cirrincione A; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Maclachlan K; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Chojnacka M; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Diamond B; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Papadimitriou M; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Blaney P; Myeloma Research Program, NYU Langone, Perlmutter Cancer Center, New York City, NY, USA., John L; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg University and German Cancer Research Center (DKFZ), Heidelberg, Germany., Reichert P; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany., Huhn S; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany., Gagler D; Myeloma Research Program, NYU Langone, Perlmutter Cancer Center, New York City, NY, USA., Zhang Y; Cytogenetics Laboratory, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Dogan A; Hematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Lesokhin AM; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Davies F; Myeloma Research Program, NYU Langone, Perlmutter Cancer Center, New York City, NY, USA., Goldschmidt H; Internal Medicine V, Hematology, Oncology and Rheumatology, GMMG Study Group, Heidelberg University Hospital and the National Center for Tumor Diseases (NCT), Heidelberg, Germany., Fenk R; Department of Hematology, Oncology and Clinical Immunology, University Hospital Duesseldorf, Duesseldorf, Germany., Weisel KC; Department of Oncology, Hematology, and Blood and Marrow Transplant, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Mai EK; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany., Korde N; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Morgan GJ; Myeloma Research Program, NYU Langone, Perlmutter Cancer Center, New York City, NY, USA., Rajkumar SV; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA., Kumar S; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA., Usmani S; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Landgren O; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Raab MS; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg University and German Cancer Research Center (DKFZ), Heidelberg, Germany., Weinhold N; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany. niels.weinhold@med.uni-heidelberg.de.; Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg University and German Cancer Research Center (DKFZ), Heidelberg, Germany. niels.weinhold@med.uni-heidelberg.de. |
| Source: | Nature genetics [Nat Genet] 2025 Sep; Vol. 57 (9), pp. 2203-2214. Date of Electronic Publication: 2025 Aug 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40835892 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Temporal genomic dynamics shape clinical trajectory in multiple myeloma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Maura+F%22">Maura F</searchLink>; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA. mauraf@mskcc.org.; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. mauraf@mskcc.org.<br /><searchLink fieldCode="AU" term="%22Kaddoura+M%22">Kaddoura M</searchLink>; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Poos+AM%22">Poos AM</searchLink>; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg University and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Baughn+LB%22">Baughn LB</searchLink>; Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Ziccheddu+B%22">Ziccheddu B</searchLink>; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Bärtsch+MA%22">Bärtsch MA</searchLink>; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg University and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Cirrincione+A%22">Cirrincione A</searchLink>; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Maclachlan+K%22">Maclachlan K</searchLink>; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chojnacka+M%22">Chojnacka M</searchLink>; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Diamond+B%22">Diamond B</searchLink>; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Papadimitriou+M%22">Papadimitriou M</searchLink>; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Blaney+P%22">Blaney P</searchLink>; Myeloma Research Program, NYU Langone, Perlmutter Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22John+L%22">John L</searchLink>; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg University and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Reichert+P%22">Reichert P</searchLink>; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Huhn+S%22">Huhn S</searchLink>; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Gagler+D%22">Gagler D</searchLink>; Myeloma Research Program, NYU Langone, Perlmutter Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Cytogenetics Laboratory, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dogan+A%22">Dogan A</searchLink>; Hematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lesokhin+AM%22">Lesokhin AM</searchLink>; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Davies+F%22">Davies F</searchLink>; Myeloma Research Program, NYU Langone, Perlmutter Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Goldschmidt+H%22">Goldschmidt H</searchLink>; Internal Medicine V, Hematology, Oncology and Rheumatology, GMMG Study Group, Heidelberg University Hospital and the National Center for Tumor Diseases (NCT), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Fenk+R%22">Fenk R</searchLink>; Department of Hematology, Oncology and Clinical Immunology, University Hospital Duesseldorf, Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Weisel+KC%22">Weisel KC</searchLink>; Department of Oncology, Hematology, and Blood and Marrow Transplant, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Mai+EK%22">Mai EK</searchLink>; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Korde+N%22">Korde N</searchLink>; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Morgan+GJ%22">Morgan GJ</searchLink>; Myeloma Research Program, NYU Langone, Perlmutter Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rajkumar+SV%22">Rajkumar SV</searchLink>; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+S%22">Kumar S</searchLink>; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Usmani+S%22">Usmani S</searchLink>; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Landgren+O%22">Landgren O</searchLink>; Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Raab+MS%22">Raab MS</searchLink>; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg University and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Weinhold+N%22">Weinhold N</searchLink>; Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Medical Faculty, Heidelberg University, Heidelberg, Germany. niels.weinhold@med.uni-heidelberg.de.; Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg University and German Cancer Research Center (DKFZ), Heidelberg, Germany. niels.weinhold@med.uni-heidelberg.de. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2025 Sep; Vol. 57 (9), pp. 2203-2214. <i>Date of Electronic Publication: </i>2025 Aug 20. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Co%22">Nature Pub. Co </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9216904 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-1718 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210614036%22">10614036 </searchLink><i>NLM ISO Abbreviation: </i>Nat Genet <i>Subsets: </i>MEDLINE |
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