Increased reflux secondary bile acids are associated with changes to the microbiome and transcriptome in Barrett's esophagus.

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Title: Increased reflux secondary bile acids are associated with changes to the microbiome and transcriptome in Barrett's esophagus.
Authors: Tanes C; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Li Y; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Falk GW; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Ginsberg GG; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Wang KK; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Iyer PG; Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA., Lightdale CJ; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA., Del Portillo A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Lagana SM; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Wang TC; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, NY, USA., Rustgi AK; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, NY, USA., Quante M; Department of Medicine II, University of Freiburg, Freiburg, Germany., Jin Z; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA., Wu GD; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Friedman ES; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bittinger K; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Li H; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Abrams JA; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, NY, USA.
Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2545420. Date of Electronic Publication: 2025 Aug 22.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1949-0984
DOI:10.1080/19490976.2025.2545420