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Increased reflux secondary bile acids are associated with changes to the microbiome and transcriptome in Barrett's esophagus.

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Title: Increased reflux secondary bile acids are associated with changes to the microbiome and transcriptome in Barrett's esophagus.
Authors: Tanes C; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Li Y; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Falk GW; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Ginsberg GG; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Wang KK; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Iyer PG; Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA., Lightdale CJ; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA., Del Portillo A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Lagana SM; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Wang TC; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, NY, USA., Rustgi AK; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, NY, USA., Quante M; Department of Medicine II, University of Freiburg, Freiburg, Germany., Jin Z; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA., Wu GD; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Friedman ES; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bittinger K; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Li H; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Abrams JA; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, NY, USA.
Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2545420. Date of Electronic Publication: 2025 Aug 22.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased reflux secondary bile acids are associated with changes to the microbiome and transcriptome in Barrett's esophagus.
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  Data: <searchLink fieldCode="AU" term="%22Tanes+C%22">Tanes C</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Falk+GW%22">Falk GW</searchLink>; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ginsberg+GG%22">Ginsberg GG</searchLink>; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+KK%22">Wang KK</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Iyer+PG%22">Iyer PG</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Lightdale+CJ%22">Lightdale CJ</searchLink>; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Del+Portillo+A%22">Del Portillo A</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lagana+SM%22">Lagana SM</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wang+TC%22">Wang TC</searchLink>; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Rustgi+AK%22">Rustgi AK</searchLink>; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Quante+M%22">Quante M</searchLink>; Department of Medicine II, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jin+Z%22">Jin Z</searchLink>; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wu+GD%22">Wu GD</searchLink>; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Friedman+ES%22">Friedman ES</searchLink>; Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bittinger+K%22">Bittinger K</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Abrams+JA%22">Abrams JA</searchLink>; Division of Digestive & Liver Diseases, Columbia University Irving Medical Center, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, NY, USA.
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  Data: <searchLink fieldCode="JN" term="%22101495343%22">Gut microbes</searchLink> [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2545420. <i>Date of Electronic Publication: </i>2025 Aug 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101495343 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1949-0984 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219490976%22">19490976 </searchLink><i>NLM ISO Abbreviation: </i>Gut Microbes <i>Subsets: </i>MEDLINE
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