Multi-omic identification of perineurial hyperplasia and lipid-associated nerve macrophages in human polyneuropathies.

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Title: Multi-omic identification of perineurial hyperplasia and lipid-associated nerve macrophages in human polyneuropathies.
Authors: Heming M; Department of Neurology, University Hospital Münster, Münster, Germany., Börsch AL; Department of Neurology, University Hospital Münster, Münster, Germany., Wolbert J; Department of Neurology, University Hospital Münster, Münster, Germany., Thomas C; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Mausberg AK; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany., Szepanowski F; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany., Eggert B; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany., Lu IN; Department of Neurology, University Hospital Münster, Münster, Germany., Tietz J; Department of Neurology, University Hospital Münster, Münster, Germany., Dienhart F; Department of Neurology, University Hospital Münster, Münster, Germany., Meschnark M; Department of Neurology, University Hospital Münster, Münster, Germany., Strecker JK; Department of Neurology, University Hospital Schleswig-Holstein, Lübeck, Germany., Glatza M; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Thomas C; Paul-Flechsig-Institute of Neuropathology, University Hospital Leipzig, Leipzig, Germany., Gmahl N; Department of Neurology, University Hospital Münster, Münster, Germany., Dambietz C; Department of Neurology, University Hospital Münster, Münster, Germany., Müther M; Department of Neurosurgery, University Hospital Münster, Münster, Germany., Uerschels AK; Department of Neurosurgery, University Hospital Essen, Essen, Germany., Keyvani K; Department of Neuropathology, University Hospital Essen, Essen, Germany., Minnerup J; Department of Neurology, University Hospital Schleswig-Holstein, Lübeck, Germany., Doppler K; Department of Neurology, University Hospital Würzburg, Würzburg, Germany., Üçeyler N; Department of Neurology, University Hospital Würzburg, Würzburg, Germany., Aprea J; DRESDEN-concept Genome Center, Center for Molecular and Cellular Bioengineering, Dresden University of Technology, Dresden, Germany., Dahl A; DRESDEN-concept Genome Center, Center for Molecular and Cellular Bioengineering, Dresden University of Technology, Dresden, Germany., Stassart R; Paul-Flechsig-Institute of Neuropathology, University Hospital Leipzig, Leipzig, Germany., Fledrich R; Institute of Anatomy, University of Leipzig, Leipzig, Germany., Wiendl H; Clinic of Neurology and Neurophysiology, University of Freiburg, Freiburg, Germany., Sommer C; Department of Neurology, University Hospital Würzburg, Würzburg, Germany., Stettner M; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences (C-TNBS), University Hospital Essen, Essen, Germany., Meyer Zu Hörste G; Department of Neurology, University Hospital Münster, Münster, Germany. gerd.meyerzuhoerste@ukmuenster.de.
Source: Nature communications [Nat Commun] 2025 Aug 23; Vol. 16 (1), pp. 7872. Date of Electronic Publication: 2025 Aug 23.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-62964-8