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Sex-specific metabolic and central effects of GLP-1-estradiol conjugate in middle-aged rats on a standard or western diet.

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Title: Sex-specific metabolic and central effects of GLP-1-estradiol conjugate in middle-aged rats on a standard or western diet.
Authors: Richard JE; Centre for Addiction and Mental Health, Toronto, ON Canada; Department of Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada., Mohammad A; Centre for Addiction and Mental Health, Toronto, ON Canada; Institute of Medical Sciences, University of Toronto, Canada., Go KA; Centre for Addiction and Mental Health, Toronto, ON Canada; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada., McGovern AJ; Centre for Addiction and Mental Health, Toronto, ON Canada., Rechlin RK; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada., Splinter TFL; Centre for Addiction and Mental Health, Toronto, ON Canada; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada., Lieblich SE; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada., Radovic LK; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada., Feng L; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada., Blankers SA; Centre for Addiction and Mental Health, Toronto, ON Canada., Yang B; Novo Nordisk Research Center Indianapolis, Inc. Indianapolis, IN, USA., Douros JD; Novo Nordisk Research Center Indianapolis, Inc. Indianapolis, IN, USA., Finan B; Novo Nordisk Research Center Indianapolis, Inc. Indianapolis, IN, USA., Galea LAM; Centre for Addiction and Mental Health, Toronto, ON Canada; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada; Institute of Medical Sciences, University of Toronto, Canada; Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada. Electronic address: liisa.galea@utoronto.ca.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2025 Nov; Vol. 130, pp. 106088. Date of Electronic Publication: 2025 Aug 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
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              Text: 2025 Nov
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