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Bcl11a deficiency in cerebellar Purkinje cells causes ataxia and autistic-like behavior by altering Vav3.

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Title: Bcl11a deficiency in cerebellar Purkinje cells causes ataxia and autistic-like behavior by altering Vav3.
Authors: Zhang J; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Li YX; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Huang Q; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Yuan Y; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Chen JY; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Yang FW; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Yang L; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Liu LY; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China. liuly@fudan.edu.cn., Yu YC; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China. ycyu@fudan.edu.cn.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Feb; Vol. 31 (2), pp. 802-818. Date of Electronic Publication: 2025 Aug 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5578
DOI:10.1038/s41380-025-03175-x