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Bcl11a deficiency in cerebellar Purkinje cells causes ataxia and autistic-like behavior by altering Vav3.

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Title: Bcl11a deficiency in cerebellar Purkinje cells causes ataxia and autistic-like behavior by altering Vav3.
Authors: Zhang J; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Li YX; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Huang Q; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Yuan Y; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Chen JY; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Yang FW; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Yang L; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Liu LY; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China. liuly@fudan.edu.cn., Yu YC; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China. ycyu@fudan.edu.cn.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Feb; Vol. 31 (2), pp. 802-818. Date of Electronic Publication: 2025 Aug 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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  Data: Bcl11a deficiency in cerebellar Purkinje cells causes ataxia and autistic-like behavior by altering Vav3.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Li+YX%22">Li YX</searchLink>; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Huang+Q%22">Huang Q</searchLink>; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Yuan+Y%22">Yuan Y</searchLink>; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Chen+JY%22">Chen JY</searchLink>; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Yang+FW%22">Yang FW</searchLink>; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Liu+LY%22">Liu LY</searchLink>; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China. liuly@fudan.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yu+YC%22">Yu YC</searchLink>; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China. ycyu@fudan.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2026 Feb; Vol. 31 (2), pp. 802-818. <i>Date of Electronic Publication: </i>2025 Aug 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41380-025-03175-x
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        Text: English
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      – TitleFull: Bcl11a deficiency in cerebellar Purkinje cells causes ataxia and autistic-like behavior by altering Vav3.
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              Text: 2026 Feb
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