Restoration of CB1 receptor function in hippocampal GABAergic neurons rescues memory deficits in Huntington's disease models.
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| Title: | Restoration of CB1 receptor function in hippocampal GABAergic neurons rescues memory deficits in Huntington's disease models. |
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| Authors: | Di Franco N; Departament de Biomedicina, Facultat de Medicina I Ciències de La Salut, Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain. nadia.difranco@ub.edu.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain. nadia.difranco@ub.edu.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain. nadia.difranco@ub.edu., Bengoetxea de Tena I; Department of Pharmacology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Spain.; Neurodegenerative Diseases, BioCruces Bizkaia Health Research Institute, Barakaldo, Spain., Sanchez-Ruiz A; Instituto Cajal, Spanish National Research Council (CSIC), Madrid, Spain., Pereda-Velarde A; Departament de Biomedicina, Facultat de Medicina I Ciències de La Salut, Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Enfedaque F; Departament de Biomedicina, Facultat de Medicina I Ciències de La Salut, Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Gónzalez-Arias C; Instituto Cajal, Spanish National Research Council (CSIC), Madrid, Spain., Rio LMM; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Department of Neurochemistry and Neuropharmacology, Instituto de Investigaciones Biomédicas de Barcelona (IIBB-CSIC), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Bortolozzi A; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Department of Neurochemistry and Neuropharmacology, Instituto de Investigaciones Biomédicas de Barcelona (IIBB-CSIC), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Rodriguez-Puertas R; Department of Pharmacology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Spain.; Neurodegenerative Diseases, BioCruces Bizkaia Health Research Institute, Barakaldo, Spain., Costas-Insua C; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Instituto Universitario de Investigación Neuroquímica (IUIN), Universidad Complutense, Madrid, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Center for Molecular Biology, Universität Heidelberg (ZMBH), Heidelberg, Germany., Molina-Porcel L; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, I Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer (FRCB-IDIBAPS), University of Barcelona, Barcelona, Spain.; Neurological Tissue Bank, Biobanc-Hospital Clínic-FRCB/IDIBAPS, Barcelona, Spain., Vazquez-Oliver A; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Movement Disorders Unit, Neurology Department, Hospital de La Santa Creu I Sant Pau, Biomedical Research Institute Sant Pau (IIB-Sant Pau), 08041, Barcelona, Spain., Ozaita A; Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain., Guzmán M; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Instituto Universitario de Investigación Neuroquímica (IUIN), Universidad Complutense, Madrid, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., Perea G; Instituto Cajal, Spanish National Research Council (CSIC), Madrid, Spain., Ginés S; Departament de Biomedicina, Facultat de Medicina I Ciències de La Salut, Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain. silviagines@ub.edu.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain. silviagines@ub.edu.; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain. silviagines@ub.edu. |
| Source: | Translational neurodegeneration [Transl Neurodegener] 2025 Aug 25; Vol. 14 (1), pp. 44. Date of Electronic Publication: 2025 Aug 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158 (Print) Linking ISSN: 20479158 NLM ISO Abbreviation: Transl Neurodegener Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2047-9158 |
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| DOI: | 10.1186/s40035-025-00500-w |
