Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins.

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Title: Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins.
Authors: Xu D; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Besselink S; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.; Molecular Mechanisms of Disease Master's Program, Radboud University, Nijmegen, the Netherlands., Ramadoss GN; Gladstone Institutes, San Francisco, CA, USA., Dierks PH; Gladstone Institutes, San Francisco, CA, USA., Lubin JP; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, USA., Pattali RK; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Brim JI; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Christenson AE; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Colias PJ; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Ornelas IJ; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Nguyen CD; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Chasins SE; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, USA.; Chan Zuckerberg Biohub San Francisco, San Francisco, CA, USA., Conklin BR; Gladstone Institutes, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, CA, USA., Nuñez JK; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. jamesnunez@berkeley.edu.; Chan Zuckerberg Biohub San Francisco, San Francisco, CA, USA. jamesnunez@berkeley.edu.
Source: Nature communications [Nat Commun] 2025 Aug 26; Vol. 16 (1), pp. 7948. Date of Electronic Publication: 2025 Aug 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-63167-x