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Synthesis and radiolabelled evaluation of novel pyrimidine derivatives as dual α-amylase inhibitors and GIT-targeted molecular imaging probe.

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Title: Synthesis and radiolabelled evaluation of novel pyrimidine derivatives as dual α-amylase inhibitors and GIT-targeted molecular imaging probe.
Authors: Elsayed DA; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt., Shehta W; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt., El-Kalyoubi S; Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Port Said University Port Said 42511 Egypt., Selim A; Labelled Compounds Department, Hot Laboratories Center, Egyptian Atomic Energy Authority P.O. Box 13759 Cairo Egypt., Assy MG; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt., Metwally O; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt., Al-Kubaisi AA; Department of Medical Laboratories Techniques, College of Health and Medical Technology, University of Al Maarif Al Anbar 31001 Iraq doaaatef641995@gmail.com., Awad SA; Department of Medical Laboratories Techniques, College of Health and Medical Technology, University of Al Maarif Al Anbar 31001 Iraq doaaatef641995@gmail.com., Marzook F; Labelled Compounds Department, Hot Laboratories Center, Egyptian Atomic Energy Authority P.O. Box 13759 Cairo Egypt.
Source: RSC advances [RSC Adv] 2025 Aug 21; Vol. 15 (36), pp. 29544-29559. Date of Electronic Publication: 2025 Aug 21 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Synthesis and radiolabelled evaluation of novel pyrimidine derivatives as dual α-amylase inhibitors and GIT-targeted molecular imaging probe.
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  Data: <searchLink fieldCode="AU" term="%22Elsayed+DA%22">Elsayed DA</searchLink>; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt.<br /><searchLink fieldCode="AU" term="%22Shehta+W%22">Shehta W</searchLink>; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt.<br /><searchLink fieldCode="AU" term="%22El-Kalyoubi+S%22">El-Kalyoubi S</searchLink>; Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Port Said University Port Said 42511 Egypt.<br /><searchLink fieldCode="AU" term="%22Selim+A%22">Selim A</searchLink>; Labelled Compounds Department, Hot Laboratories Center, Egyptian Atomic Energy Authority P.O. Box 13759 Cairo Egypt.<br /><searchLink fieldCode="AU" term="%22Assy+MG%22">Assy MG</searchLink>; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt.<br /><searchLink fieldCode="AU" term="%22Metwally+O%22">Metwally O</searchLink>; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt.<br /><searchLink fieldCode="AU" term="%22Al-Kubaisi+AA%22">Al-Kubaisi AA</searchLink>; Department of Medical Laboratories Techniques, College of Health and Medical Technology, University of Al Maarif Al Anbar 31001 Iraq doaaatef641995@gmail.com.<br /><searchLink fieldCode="AU" term="%22Awad+SA%22">Awad SA</searchLink>; Department of Medical Laboratories Techniques, College of Health and Medical Technology, University of Al Maarif Al Anbar 31001 Iraq doaaatef641995@gmail.com.<br /><searchLink fieldCode="AU" term="%22Marzook+F%22">Marzook F</searchLink>; Labelled Compounds Department, Hot Laboratories Center, Egyptian Atomic Energy Authority P.O. Box 13759 Cairo Egypt.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Royal+Society+of+Chemistry%22">Royal Society of Chemistry </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101581657 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2046-2069 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220462069%22">20462069 </searchLink><i>NLM ISO Abbreviation: </i>RSC Adv <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1039/d5ra04955e
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        Text: English
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      – TitleFull: Synthesis and radiolabelled evaluation of novel pyrimidine derivatives as dual α-amylase inhibitors and GIT-targeted molecular imaging probe.
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              Text: 2025 Aug 21
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