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An immune-focused supplemental alignment pipeline captures information missed from dominant single-cell RNA-seq analyses, including allele-specific MHC-I regulation.

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Title: An immune-focused supplemental alignment pipeline captures information missed from dominant single-cell RNA-seq analyses, including allele-specific MHC-I regulation.
Authors: Benjamin S; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States., McElfresh GW; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States., Kaza M; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States., Boggy GJ; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States., Varco-Merth B; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Ojha S; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Feltham S; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Goodwin W; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Nkoy C; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Duell D; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Selseth A; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Bennett T; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Barber-Axthelm A; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Haese NN; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Wu H; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States., Waytashek C; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States., Boyle C; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States., Smedley JV; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Labriola CS; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Axthelm MK; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Reeves RK; Division of Innate and Comparative Immunology, Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States., Streblow DN; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Sacha JB; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Okoye AA; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Hansen SG; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Picker LJ; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States., Bimber BN; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, United States.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, United States.
Source: Frontiers in immunology [Front Immunol] 2025 Aug 08; Vol. 16, pp. 1596760. Date of Electronic Publication: 2025 Aug 08 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: An immune-focused supplemental alignment pipeline captures information missed from dominant single-cell RNA-seq analyses, including allele-specific MHC-I regulation.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2025 Aug 08; Vol. 16, pp. 1596760. <i>Date of Electronic Publication: </i>2025 Aug 08 (<i>Print Publication: </i>2025).
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