Peripherally administered androgen receptor-targeted antisense oligonucleotide rescues spinal pathology in a murine SBMA model.

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Bibliographic Details
Title: Peripherally administered androgen receptor-targeted antisense oligonucleotide rescues spinal pathology in a murine SBMA model.
Authors: Lee C; Interdepartmental Neuroscience Program, Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut, USA., Yu Z; Department of Pathology and., Kuo CJ; Department of Pathology and.; Cellular and Molecular Biology Graduate Program, Medical Scientist Training Program, University of Michigan Medical School, Ann Arbor, Michigan, USA., Tejwani L; Interdepartmental Neuroscience Program, Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut, USA., Grijalva RM; Interdepartmental Neuroscience Program, Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut, USA., Bae E; Department of Genetics, Yale School of Medicine, New Haven, Connecticut, USA., Zhao HT; Ionis Pharmaceuticals Inc., Carlsbad, California, USA., Lim J; Interdepartmental Neuroscience Program, Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Genetics, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut, USA., Lieberman AP; Department of Pathology and.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Aug 28; Vol. 135 (21). Date of Electronic Publication: 2025 Aug 28 (Print Publication: 2025).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-8238
DOI:10.1172/JCI182955