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Integrating breast cancer polygenic risk scores at scale in the WISDOM Study: a national randomized personalized screening trial.

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Title: Integrating breast cancer polygenic risk scores at scale in the WISDOM Study: a national randomized personalized screening trial.
Authors: Fergus KB; Department of Surgery, University of California, San Francisco, CA, USA., Heise RS; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA., Madlensky L; Department of Medicine, University of California, San Diego, CA, USA., Fiscalini A; Department of Surgery, University of California, San Francisco, CA, USA., Sabacan L; Department of Surgery, University of California, San Francisco, CA, USA., Theiner S; Department of Medicine, Santa Clara Valley Medical Center, San Jose, CA, USA., Kapoor S; Department of Surgery, University of California, San Francisco, CA, USA., Soto IA; Department of Surgery, University of California, San Francisco, CA, USA., Blanco A; Department of Cancer Genetics and Prevention, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Ross K; Department of Cancer Genetics and Prevention, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Goodman-Gruen D; Department of Epidemiology and Biostatistics, University of California, Irvine, CA, USA., Scheuner M; Department of Medicine, University of California, San Francisco, CA, USA., Hu D; Department of Medicine, University of California, San Francisco, CA, USA., Heditsian D; Breast Oncology Program, Breast Science Advocacy Core, University of California, San Francisco, CA, USA., Brain S; Breast Oncology Program, Breast Science Advocacy Core, University of California, San Francisco, CA, USA., Arasu VA; Kaiser Permanente Division of Research, Pleasanton, CA, USA., Kaster A; Sanford Health, Sioux Falls, SD, USA., Chapa L; Doctors Hospital at Renaissance, Edinburg, TX, USA., Olopade OI; Center for Clinical Cancer Genetics and Global Health, Department of Medicine, The University of Chicago, Chicago, IL, USA., Eklund M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Tice JA; Department of Medicine, University of California, San Francisco, CA, USA., Ziv E; Department of Medicine, University of California, San Francisco, CA, USA., van 't Veer L; Department of Laboratory Medicine, University of California, San Francisco, CA, USA., Esserman LJ; Department of Surgery, University of California, San Francisco, CA, USA., Shieh Y; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA. yis4001@med.cornell.edu.
Corporate Authors: Athena/WISDOM Network Collaborators and Advocate Partners
Source: Genome medicine [Genome Med] 2025 Aug 28; Vol. 17 (1), pp. 97. Date of Electronic Publication: 2025 Aug 28.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrating breast cancer polygenic risk scores at scale in the WISDOM Study: a national randomized personalized screening trial.
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  Data: <searchLink fieldCode="AU" term="%22Fergus+KB%22">Fergus KB</searchLink>; Department of Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Heise+RS%22">Heise RS</searchLink>; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Madlensky+L%22">Madlensky L</searchLink>; Department of Medicine, University of California, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fiscalini+A%22">Fiscalini A</searchLink>; Department of Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sabacan+L%22">Sabacan L</searchLink>; Department of Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Theiner+S%22">Theiner S</searchLink>; Department of Medicine, Santa Clara Valley Medical Center, San Jose, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kapoor+S%22">Kapoor S</searchLink>; Department of Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Soto+IA%22">Soto IA</searchLink>; Department of Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Blanco+A%22">Blanco A</searchLink>; Department of Cancer Genetics and Prevention, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ross+K%22">Ross K</searchLink>; Department of Cancer Genetics and Prevention, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Goodman-Gruen+D%22">Goodman-Gruen D</searchLink>; Department of Epidemiology and Biostatistics, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Scheuner+M%22">Scheuner M</searchLink>; Department of Medicine, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hu+D%22">Hu D</searchLink>; Department of Medicine, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Heditsian+D%22">Heditsian D</searchLink>; Breast Oncology Program, Breast Science Advocacy Core, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Brain+S%22">Brain S</searchLink>; Breast Oncology Program, Breast Science Advocacy Core, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Arasu+VA%22">Arasu VA</searchLink>; Kaiser Permanente Division of Research, Pleasanton, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kaster+A%22">Kaster A</searchLink>; Sanford Health, Sioux Falls, SD, USA.<br /><searchLink fieldCode="AU" term="%22Chapa+L%22">Chapa L</searchLink>; Doctors Hospital at Renaissance, Edinburg, TX, USA.<br /><searchLink fieldCode="AU" term="%22Olopade+OI%22">Olopade OI</searchLink>; Center for Clinical Cancer Genetics and Global Health, Department of Medicine, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Eklund+M%22">Eklund M</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Tice+JA%22">Tice JA</searchLink>; Department of Medicine, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ziv+E%22">Ziv E</searchLink>; Department of Medicine, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22van+'t+Veer+L%22">van 't Veer L</searchLink>; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Esserman+LJ%22">Esserman LJ</searchLink>; Department of Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shieh+Y%22">Shieh Y</searchLink>; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA. yis4001@med.cornell.edu.
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  Data: <searchLink fieldCode="JN" term="%22101475844%22">Genome medicine</searchLink> [Genome Med] 2025 Aug 28; Vol. 17 (1), pp. 97. <i>Date of Electronic Publication: </i>2025 Aug 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101475844 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1756-994X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221756994X%22">1756994X </searchLink><i>NLM ISO Abbreviation: </i>Genome Med <i>Subsets: </i>MEDLINE
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