Knockdown of Derlin-1 Represses Cellular Oncogenic Activities in Uveal Melanoma, Enhances its Chemosensitivity to Cisplatin and Reduces Cancer Stem Cell Potential.

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Title: Knockdown of Derlin-1 Represses Cellular Oncogenic Activities in Uveal Melanoma, Enhances its Chemosensitivity to Cisplatin and Reduces Cancer Stem Cell Potential.
Authors: Hsieh MY; Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, R.O.C.; Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C., Chen JR; Division of Pulmonary & Respiratory Medicine, Department of Internal Medicine, E-Da Cancer Hospital, I-Shou University, Kaohsiung, Taiwan, R.O.C., Tsai PC; Division of Thoracic Surgery, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C.; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, R.O.C., Chen CY; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C., Liu AC; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C., Yeh HY; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C., Chen WT; Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, R.O.C.; Department of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C., Wu CY; Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, R.O.C.; cywu@mail.nsysu.edu.tw raymond.pinus@vghks.gov.tw.; Department of Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C., Li SC; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C.; cywu@mail.nsysu.edu.tw raymond.pinus@vghks.gov.tw.; Center of General Education, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan, R.O.C.
Source: Cancer genomics & proteomics [Cancer Genomics Proteomics] 2025 Sep-Oct; Vol. 22 (5), pp. 809-823.
Publication Type: Journal Article
Journal Info: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 101188791 Publication Model: Print Cited Medium: Internet ISSN: 1790-6245 (Electronic) Linking ISSN: 11096535 NLM ISO Abbreviation: Cancer Genomics Proteomics Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1790-6245
DOI:10.21873/cgp.20538