Ceftriaxone to Prevent Early-Onset Pneumonia in Comatose Patients Following Out-of-Hospital Cardiac Arrest: A Pilot Randomized Controlled Trial and Resistome Assessment (PROTECT).

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Bibliographic Details
Title: Ceftriaxone to Prevent Early-Onset Pneumonia in Comatose Patients Following Out-of-Hospital Cardiac Arrest: A Pilot Randomized Controlled Trial and Resistome Assessment (PROTECT).
Authors: Gagnon DJ; Department of Pharmacy, Maine Medical Center, Portland, ME; MaineHealth Institute for Research, Scarborough, ME; Tufts University School of Medicine, Boston, MA. Electronic address: David.Gagnon@mainehealth.org., Burkholder KM; School of Biological Sciences, University of New England, Biddeford, ME., Weissman AJ; Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA., Riker RR; Department of Critical Care Services, Maine Medical Center, Portland, ME; Tufts University School of Medicine, Boston, MA., Ryzhov S; MaineHealth Institute for Research, Scarborough, ME., May TL; Department of Critical Care Services, Maine Medical Center, Portland, ME; MaineHealth Institute for Research, Scarborough, ME; Tufts University School of Medicine, Boston, MA., DiPalazzo J; MaineHealth Institute for Research, Scarborough, ME., deKay JT; MaineHealth Institute for Research, Scarborough, ME., Knudsen L; MaineHealth Institute for Research, Scarborough, ME., Moore MW; Department of Critical Care Services, Maine Medical Center, Portland, ME; Tufts University School of Medicine, Boston, MA., Pozzessere NA; Department of Critical Care Services, Maine Medical Center, Portland, ME., Weatherbee M; MaineHealth Institute for Research, Scarborough, ME., Kelly M; Hubbard Center for Genome Studies, University of New Hampshire, Durham, NH., Nigatu AS; Hubbard Center for Genome Studies, University of New Hampshire, Durham, NH., Sevigny JL; Hubbard Center for Genome Studies, University of New Hampshire, Durham, NH., Simpson S; Hubbard Center for Genome Studies, University of New Hampshire, Durham, NH., Thomas WK; Hubbard Center for Genome Studies, University of New Hampshire, Durham, NH., Callaway CW; Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA., Geller BJ; Department of Cardiovascular Services, Maine Medical Center, Portland, ME., Sawyer DB; Department of Cardiovascular Services, Maine Medical Center, Portland, ME; MaineHealth Institute for Research, Scarborough, ME; Tufts University School of Medicine, Boston, MA., Seder DB; Department of Critical Care Services, Maine Medical Center, Portland, ME; MaineHealth Institute for Research, Scarborough, ME; Tufts University School of Medicine, Boston, MA.
Source: Chest [Chest] 2026 Jan; Vol. 169 (1), pp. 115-127. Date of Electronic Publication: 2025 Aug 28.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0231335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-3543 (Electronic) Linking ISSN: 00123692 NLM ISO Abbreviation: Chest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1931-3543
DOI:10.1016/j.chest.2025.08.007