View in EDS

Loss of Necdin causes social deficit and aberrant synaptic function through destabilization of SynGAP.

Saved in:
Bibliographic Details
Title: Loss of Necdin causes social deficit and aberrant synaptic function through destabilization of SynGAP.
Authors: Li X; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Medical Genetics, Changsha, 410078, Hunan, P. R. China.; Hunan International Scientific and Technological Cooperation Base of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China., Bader I; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China., Li X; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Medical Genetics, Changsha, 410078, Hunan, P. R. China.; Hunan International Scientific and Technological Cooperation Base of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China., Lu R; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China., Liu D; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Medical Genetics, Changsha, 410078, Hunan, P. R. China.; Hunan International Scientific and Technological Cooperation Base of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China., Chen Z; Department of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China., Deng S; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Medical Genetics, Changsha, 410078, Hunan, P. R. China.; Hunan International Scientific and Technological Cooperation Base of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China., Shu Y; Department of Neurosurgery, Jinshan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, Institute for Translational Brain Research, Fudan University, Shanghai, 200032, China., Liu H; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China. huadie.liu@usc.edu.cn.; Department of Cell Biology and Genetics, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, P. R. China. huadie.liu@usc.edu.cn., Zhang J; Department of Laboratory Animals, Central South University, Changsha, Hunan, China. jingzhang@csu.edu.cn., Li JD; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China. lijiada@sklmg.edu.cn.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China. lijiada@sklmg.edu.cn.; Hunan Key Laboratory of Medical Genetics, Changsha, 410078, Hunan, P. R. China. lijiada@sklmg.edu.cn.; Hunan International Scientific and Technological Cooperation Base of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China. lijiada@sklmg.edu.cn.; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China. lijiada@sklmg.edu.cn.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Feb; Vol. 31 (2), pp. 895-907. Date of Electronic Publication: 2025 Aug 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40885846
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Loss of Necdin causes social deficit and aberrant synaptic function through destabilization of SynGAP.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Medical Genetics, Changsha, 410078, Hunan, P. R. China.; Hunan International Scientific and Technological Cooperation Base of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Bader+I%22">Bader I</searchLink>; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Medical Genetics, Changsha, 410078, Hunan, P. R. China.; Hunan International Scientific and Technological Cooperation Base of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Lu+R%22">Lu R</searchLink>; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Medical Genetics, Changsha, 410078, Hunan, P. R. China.; Hunan International Scientific and Technological Cooperation Base of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.<br /><searchLink fieldCode="AU" term="%22Deng+S%22">Deng S</searchLink>; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; Hunan Key Laboratory of Medical Genetics, Changsha, 410078, Hunan, P. R. China.; Hunan International Scientific and Technological Cooperation Base of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China.; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Shu+Y%22">Shu Y</searchLink>; Department of Neurosurgery, Jinshan Hospital, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, Institute for Translational Brain Research, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China. huadie.liu@usc.edu.cn.; Department of Cell Biology and Genetics, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, P. R. China. huadie.liu@usc.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Laboratory Animals, Central South University, Changsha, Hunan, China. jingzhang@csu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Li+JD%22">Li JD</searchLink>; Furong Laboratory, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, P. R. China. lijiada@sklmg.edu.cn.; Hunan Key Laboratory of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China. lijiada@sklmg.edu.cn.; Hunan Key Laboratory of Medical Genetics, Changsha, 410078, Hunan, P. R. China. lijiada@sklmg.edu.cn.; Hunan International Scientific and Technological Cooperation Base of Animal Models for Human Diseases, Changsha, 410078, Hunan, P. R. China. lijiada@sklmg.edu.cn.; MOE Key Laboratory of Rare Pediatric Diseases, Changsha, 410078, Hunan, P. R. China. lijiada@sklmg.edu.cn.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2026 Feb; Vol. 31 (2), pp. 895-907. <i>Date of Electronic Publication: </i>2025 Aug 30.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40885846
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41380-025-03187-7
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 895
    Titles:
      – TitleFull: Loss of Necdin causes social deficit and aberrant synaptic function through destabilization of SynGAP.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Li X
      – PersonEntity:
          Name:
            NameFull: Bader I
      – PersonEntity:
          Name:
            NameFull: Li X
      – PersonEntity:
          Name:
            NameFull: Lu R
      – PersonEntity:
          Name:
            NameFull: Liu D
      – PersonEntity:
          Name:
            NameFull: Chen Z
      – PersonEntity:
          Name:
            NameFull: Deng S
      – PersonEntity:
          Name:
            NameFull: Shu Y
      – PersonEntity:
          Name:
            NameFull: Liu H
      – PersonEntity:
          Name:
            NameFull: Zhang J
      – PersonEntity:
          Name:
            NameFull: Li JD
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: 2026 Feb
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1476-5578
          Numbering:
            – Type: volume
              Value: 31
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Molecular psychiatry
              Type: main
ResultId 1