Selective disruption of DNMT1/ELK1 interactions induces DGKI re-expression and promotes temozolomide sensitivity of MGMTmethylated/DGKImethylated glioblastoma.
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| Title: | Selective disruption of DNMT1/ELK1 interactions induces DGKI re-expression and promotes temozolomide sensitivity of MGMTmethylated/DGKImethylated glioblastoma. |
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| Authors: | Besson JM; Institut Des Biomolécules Max Mousseron, CNRS, UM, ENSCM IBMM-UMR 5247, 1919 Route de Mende, 34293Cedex 5, Montpellier, France., Etcheverry A; Molecular Genetics and Genomics Department, CHU Rennes, 35033, Rennes, France., Nadaradjane A; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France., Bougras-Cartron G; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France.; Institut de Cancérologie de L'Ouest, 44805, Saint-Herblain, France., Aubry M; INSERM, OSS (Oncogenesis Stress Signaling), UMR_S 1242, CLCC Eugene Marquis, Univ Rennes, 35000, Rennes, France., Frenel JS; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France.; Institut de Cancérologie de L'Ouest, 44805, Saint-Herblain, France., Chevanieu A; Institut Des Biomolécules Max Mousseron, CNRS, UM, ENSCM IBMM-UMR 5247, 1919 Route de Mende, 34293Cedex 5, Montpellier, France., Lopez M; Institut Des Biomolécules Max Mousseron, CNRS, UM, ENSCM IBMM-UMR 5247, 1919 Route de Mende, 34293Cedex 5, Montpellier, France., Mosser J; Molecular Genetics and Genomics Department, CHU Rennes, 35033, Rennes, France.; INSERM, OSS (Oncogenesis Stress Signaling), UMR_S 1242, CLCC Eugene Marquis, Univ Rennes, 35000, Rennes, France., Cartron PF; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, F-44000, Nantes, France. pierre-francois.cartron@inserm.fr.; Institut de Cancérologie de L'Ouest, 44805, Saint-Herblain, France. pierre-francois.cartron@inserm.fr. |
| Source: | Clinical epigenetics [Clin Epigenetics] 2025 Aug 30; Vol. 17 (1), pp. 146. Date of Electronic Publication: 2025 Aug 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Biomed Central Country of Publication: Germany NLM ID: 101516977 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-7083 (Electronic) Linking ISSN: 18687075 NLM ISO Abbreviation: Clin Epigenetics Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1868-7083 |
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| DOI: | 10.1186/s13148-025-01943-8 |