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Tuning of G-CSFR signaling by de novo-designed agonists.

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Title: Tuning of G-CSFR signaling by de novo-designed agonists.
Authors: Ullrich T; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany; Friedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany., Pollmann C; Department of Biology/Chemistry and Center for Cellular Nanoanalytics, Osnabrück University, 49076 Osnabrück, Germany., Ritter M; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany., Haaf J; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany., Aghaallaei N; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany., Tesakov I; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany., Hatskovska V; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany., El-Riz M; Department of Biology/Chemistry and Center for Cellular Nanoanalytics, Osnabrück University, 49076 Osnabrück, Germany., Maksymenko K; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany; Friedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany., Kandabarau S; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany., Klimiankou M; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany., Lengerke C; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany; German Cancer Consortium (DKTK) partner site Tübingen, a partnership between DKFZ and University Hospital Tübingen, Tübingen, Germany., Welte K; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany; University Children's Hospital Tübingen, 72076 Tübingen, Germany., Hernandez-Alvarez B; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany., Müller P; Friedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany., Lupas A; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany., Piehler J; Department of Biology/Chemistry and Center for Cellular Nanoanalytics, Osnabrück University, 49076 Osnabrück, Germany., Skokowa J; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany. Electronic address: julia.skokowa@med.uni-tuebingen.de., ElGamacy M; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany; Friedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany. Electronic address: mohammad.elgamacy@med.uni-tuebingen.de.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2025 Nov 05; Vol. 33 (11), pp. 5741-5759. Date of Electronic Publication: 2025 Aug 29.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tuning of G-CSFR signaling by de novo-designed agonists.
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  Data: <searchLink fieldCode="AU" term="%22Ullrich+T%22">Ullrich T</searchLink>; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany; Friedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Pollmann+C%22">Pollmann C</searchLink>; Department of Biology/Chemistry and Center for Cellular Nanoanalytics, Osnabrück University, 49076 Osnabrück, Germany.<br /><searchLink fieldCode="AU" term="%22Ritter+M%22">Ritter M</searchLink>; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Haaf+J%22">Haaf J</searchLink>; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Aghaallaei+N%22">Aghaallaei N</searchLink>; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Tesakov+I%22">Tesakov I</searchLink>; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hatskovska+V%22">Hatskovska V</searchLink>; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22El-Riz+M%22">El-Riz M</searchLink>; Department of Biology/Chemistry and Center for Cellular Nanoanalytics, Osnabrück University, 49076 Osnabrück, Germany.<br /><searchLink fieldCode="AU" term="%22Maksymenko+K%22">Maksymenko K</searchLink>; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany; Friedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Kandabarau+S%22">Kandabarau S</searchLink>; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Klimiankou+M%22">Klimiankou M</searchLink>; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Lengerke+C%22">Lengerke C</searchLink>; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany; German Cancer Consortium (DKTK) partner site Tübingen, a partnership between DKFZ and University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Welte+K%22">Welte K</searchLink>; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany; University Children's Hospital Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hernandez-Alvarez+B%22">Hernandez-Alvarez B</searchLink>; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+P%22">Müller P</searchLink>; Friedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Lupas+A%22">Lupas A</searchLink>; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Piehler+J%22">Piehler J</searchLink>; Department of Biology/Chemistry and Center for Cellular Nanoanalytics, Osnabrück University, 49076 Osnabrück, Germany.<br /><searchLink fieldCode="AU" term="%22Skokowa+J%22">Skokowa J</searchLink>; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany. Electronic address: julia.skokowa@med.uni-tuebingen.de.<br /><searchLink fieldCode="AU" term="%22ElGamacy+M%22">ElGamacy M</searchLink>; Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany; Friedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany; Internal Medicine II, University Hospital Tübingen, 72076 Tübingen, Germany. Electronic address: mohammad.elgamacy@med.uni-tuebingen.de.
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  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2025 Nov 05; Vol. 33 (11), pp. 5741-5759. <i>Date of Electronic Publication: </i>2025 Aug 29.
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