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Comprehensive profiling of RNA modification-related genes identifies RNA m7G binding protein CBP20 as a therapeutic target for tumor growth inhibition.

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Title: Comprehensive profiling of RNA modification-related genes identifies RNA m7G binding protein CBP20 as a therapeutic target for tumor growth inhibition.
Authors: Cho Y; Department of Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee SE; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Oh J; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Jang D; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Shin S; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee SJ; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim J; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Yang Y; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim D; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Jung HR; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Oh Y; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Park YB; Calici Co., Ltd., San Jose, CA, USA.; Calici Co., Ltd., Daejeon, Republic of Korea., Choi JM; Calici Co., Ltd., San Jose, CA, USA.; Calici Co., Ltd., Daejeon, Republic of Korea.; Department of Food and Biotechnology, Korea University, Sejong, Republic of Korea.; Department of Bio AI Convergence, Chungnam National University, Daejeon, Republic of Korea., Cho SY; Department of Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea. csybio@snu.ac.kr.
Source: Experimental & molecular medicine [Exp Mol Med] 2025 Sep; Vol. 57 (9), pp. 1978-1995. Date of Electronic Publication: 2025 Sep 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-6413 (Electronic) Linking ISSN: 12263613 NLM ISO Abbreviation: Exp Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2092-6413
DOI:10.1038/s12276-025-01531-z