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Comprehensive profiling of RNA modification-related genes identifies RNA m7G binding protein CBP20 as a therapeutic target for tumor growth inhibition.

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Title: Comprehensive profiling of RNA modification-related genes identifies RNA m7G binding protein CBP20 as a therapeutic target for tumor growth inhibition.
Authors: Cho Y; Department of Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee SE; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Oh J; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Jang D; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Shin S; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee SJ; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim J; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Yang Y; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim D; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Jung HR; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Oh Y; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Park YB; Calici Co., Ltd., San Jose, CA, USA.; Calici Co., Ltd., Daejeon, Republic of Korea., Choi JM; Calici Co., Ltd., San Jose, CA, USA.; Calici Co., Ltd., Daejeon, Republic of Korea.; Department of Food and Biotechnology, Korea University, Sejong, Republic of Korea.; Department of Bio AI Convergence, Chungnam National University, Daejeon, Republic of Korea., Cho SY; Department of Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea. csybio@snu.ac.kr.
Source: Experimental & molecular medicine [Exp Mol Med] 2025 Sep; Vol. 57 (9), pp. 1978-1995. Date of Electronic Publication: 2025 Sep 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-6413 (Electronic) Linking ISSN: 12263613 NLM ISO Abbreviation: Exp Mol Med Subsets: MEDLINE
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  Data: Comprehensive profiling of RNA modification-related genes identifies RNA m<superscript>7</superscript>G binding protein CBP20 as a therapeutic target for tumor growth inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Cho+Y%22">Cho Y</searchLink>; Department of Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SE%22">Lee SE</searchLink>; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Oh+J%22">Oh J</searchLink>; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jang+D%22">Jang D</searchLink>; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+S%22">Shin S</searchLink>; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SJ%22">Lee SJ</searchLink>; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+D%22">Kim D</searchLink>; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+HR%22">Jung HR</searchLink>; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Oh+Y%22">Oh Y</searchLink>; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+YB%22">Park YB</searchLink>; Calici Co., Ltd., San Jose, CA, USA.; Calici Co., Ltd., Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+JM%22">Choi JM</searchLink>; Calici Co., Ltd., San Jose, CA, USA.; Calici Co., Ltd., Daejeon, Republic of Korea.; Department of Food and Biotechnology, Korea University, Sejong, Republic of Korea.; Department of Bio AI Convergence, Chungnam National University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+SY%22">Cho SY</searchLink>; Department of Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. csybio@snu.ac.kr.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea. csybio@snu.ac.kr.
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