Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation.

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Title: Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation.
Authors: Martinez P; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Jury-Garfe N; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Patel H; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., You Y; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Perkins A; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., You Y; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Lee-Gosselin A; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Vidal R; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Lasagna-Reeves CA; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.
Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2025 Oct; Vol. 107 (4), pp. 1706-1720. Date of Electronic Publication: 2025 Sep 01.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1875-8908
DOI:10.1177/13872877251372603