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Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation.

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Title: Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation.
Authors: Martinez P; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Jury-Garfe N; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Patel H; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., You Y; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Perkins A; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., You Y; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Lee-Gosselin A; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Vidal R; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Lasagna-Reeves CA; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.
Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2025 Oct; Vol. 107 (4), pp. 1706-1720. Date of Electronic Publication: 2025 Sep 01.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation.
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  Data: <searchLink fieldCode="AU" term="%22Martinez+P%22">Martinez P</searchLink>; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Jury-Garfe+N%22">Jury-Garfe N</searchLink>; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Patel+H%22">Patel H</searchLink>; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22You+Y%22">You Y</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Perkins+A%22">Perkins A</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22You+Y%22">You Y</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Lee-Gosselin+A%22">Lee-Gosselin A</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Vidal+R%22">Vidal R</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Lasagna-Reeves+CA%22">Lasagna-Reeves CA</searchLink>; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.
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  Data: <searchLink fieldCode="JN" term="%229814863%22">Journal of Alzheimer's disease : JAD</searchLink> [J Alzheimers Dis] 2025 Oct; Vol. 107 (4), pp. 1706-1720. <i>Date of Electronic Publication: </i>2025 Sep 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9814863 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1875-8908 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213872877%22">13872877 </searchLink><i>NLM ISO Abbreviation: </i>J Alzheimers Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1177/13872877251372603
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      – Code: eng
        Text: English
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        StartPage: 1706
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      – TitleFull: Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation.
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              Text: 2025 Oct
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              Y: 2025
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