ECM-Induced IL-23 Drives Immune Suppression in Breast Cancer via Regulating PD-1 on Tregs.
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| Title: | ECM-Induced IL-23 Drives Immune Suppression in Breast Cancer via Regulating PD-1 on Tregs. |
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| Authors: | Talarico G; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.; Laboratory of Hematology-Oncology, European Institute of Oncology IRCCS, Milan, Italy., Lecchi M; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milan, Italy., Zanichelli A; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Portararo P; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Botti L; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Cappelletti V; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Costanza M; Neuroimmunology and Neuromuscular Diseases Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Piva A; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.; Department of Experimental Oncology, European Institute of Oncology, Milan, Italy., Pratesi P; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milan, Italy., Bertolini F; Laboratory of Hematology-Oncology, European Institute of Oncology IRCCS, Milan, Italy., Di Nicola M; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Tripodo C; Tumor Immunology Unit, Department of Health Sciences, University of Palermo, Palermo, Italy., Cancila V; Tumor Immunology Unit, Department of Health Sciences, University of Palermo, Palermo, Italy., Pupa SM; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Colombo MP; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Chiodoni C; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Verderio P; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milan, Italy., Sangaletti S; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy. sabina.sangaletti@istitutotumori.mi.it. |
| Source: | Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2025 Sep 01; Vol. 44 (1), pp. 264. Date of Electronic Publication: 2025 Sep 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966 (Electronic) Linking ISSN: 03929078 NLM ISO Abbreviation: J Exp Clin Cancer Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1756-9966 |
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| DOI: | 10.1186/s13046-025-03518-0 |
