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ECM-Induced IL-23 Drives Immune Suppression in Breast Cancer via Regulating PD-1 on Tregs.

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Title: ECM-Induced IL-23 Drives Immune Suppression in Breast Cancer via Regulating PD-1 on Tregs.
Authors: Talarico G; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.; Laboratory of Hematology-Oncology, European Institute of Oncology IRCCS, Milan, Italy., Lecchi M; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milan, Italy., Zanichelli A; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Portararo P; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Botti L; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Cappelletti V; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Costanza M; Neuroimmunology and Neuromuscular Diseases Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Piva A; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.; Department of Experimental Oncology, European Institute of Oncology, Milan, Italy., Pratesi P; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milan, Italy., Bertolini F; Laboratory of Hematology-Oncology, European Institute of Oncology IRCCS, Milan, Italy., Di Nicola M; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Tripodo C; Tumor Immunology Unit, Department of Health Sciences, University of Palermo, Palermo, Italy., Cancila V; Tumor Immunology Unit, Department of Health Sciences, University of Palermo, Palermo, Italy., Pupa SM; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Colombo MP; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Chiodoni C; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy., Verderio P; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milan, Italy., Sangaletti S; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy. sabina.sangaletti@istitutotumori.mi.it.
Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2025 Sep 01; Vol. 44 (1), pp. 264. Date of Electronic Publication: 2025 Sep 01.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966 (Electronic) Linking ISSN: 03929078 NLM ISO Abbreviation: J Exp Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ECM-Induced IL-23 Drives Immune Suppression in Breast Cancer via Regulating PD-1 on Tregs.
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  Data: <searchLink fieldCode="AU" term="%22Talarico+G%22">Talarico G</searchLink>; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.; Laboratory of Hematology-Oncology, European Institute of Oncology IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lecchi+M%22">Lecchi M</searchLink>; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Zanichelli+A%22">Zanichelli A</searchLink>; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Portararo+P%22">Portararo P</searchLink>; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Botti+L%22">Botti L</searchLink>; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cappelletti+V%22">Cappelletti V</searchLink>; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Costanza+M%22">Costanza M</searchLink>; Neuroimmunology and Neuromuscular Diseases Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Piva+A%22">Piva A</searchLink>; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.; Department of Experimental Oncology, European Institute of Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pratesi+P%22">Pratesi P</searchLink>; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bertolini+F%22">Bertolini F</searchLink>; Laboratory of Hematology-Oncology, European Institute of Oncology IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Nicola+M%22">Di Nicola M</searchLink>; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tripodo+C%22">Tripodo C</searchLink>; Tumor Immunology Unit, Department of Health Sciences, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Cancila+V%22">Cancila V</searchLink>; Tumor Immunology Unit, Department of Health Sciences, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Pupa+SM%22">Pupa SM</searchLink>; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Colombo+MP%22">Colombo MP</searchLink>; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Chiodoni+C%22">Chiodoni C</searchLink>; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Verderio+P%22">Verderio P</searchLink>; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sangaletti+S%22">Sangaletti S</searchLink>; Molecular Immunology Unit, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy. sabina.sangaletti@istitutotumori.mi.it.
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  Data: <searchLink fieldCode="JN" term="%228308647%22">Journal of experimental & clinical cancer research : CR</searchLink> [J Exp Clin Cancer Res] 2025 Sep 01; Vol. 44 (1), pp. 264. <i>Date of Electronic Publication: </i>2025 Sep 01.
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