Comparative metabolomic analysis of human lung slices (hu-PCLS) exposed to either standard or FLASH protons: a pilot study.

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Title: Comparative metabolomic analysis of human lung slices (hu-PCLS) exposed to either standard or FLASH protons: a pilot study.
Authors: Velalopoulou A; Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104, USA., Mak TD; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA.; Mass Spectrometry Data Center, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA., Deziel A; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA., Kim MM; Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104, USA., Koumenis C; Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104, USA., Christofidou-Solomidou M; Division of Pulmonary, Department of Medicine, Allergy, and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Laiakis EC; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA. ecl28@georgetown.edu.; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, DC, 20057, USA. ecl28@georgetown.edu.; Department of Radiation Medicine, Georgetown University, Washington, DC, 20057, USA. ecl28@georgetown.edu.; Center for Metabolomic Studies, Georgetown University, Washington, DC, 20057, USA. ecl28@georgetown.edu.
Source: Radiation oncology (London, England) [Radiat Oncol] 2025 Sep 02; Vol. 20 (1), pp. 138. Date of Electronic Publication: 2025 Sep 02.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101265111 Publication Model: Electronic Cited Medium: Internet ISSN: 1748-717X (Electronic) Linking ISSN: 1748717X NLM ISO Abbreviation: Radiat Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1748-717X
DOI:10.1186/s13014-025-02714-8