Targeting mitochondrial proteases CLPP and LONP1 via disruption of mitochondrial redox homeostasis induces proteotoxic stress and suppresses tumor progression.
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| Title: | Targeting mitochondrial proteases CLPP and LONP1 via disruption of mitochondrial redox homeostasis induces proteotoxic stress and suppresses tumor progression. |
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| Authors: | Nandha SR; Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India., Patwardhan RS; Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India., Sharma D; Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India., Sandur SK; Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India. sskumar@barc.gov.in.; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India. sskumar@barc.gov.in., Checker R; Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India. rchecker@barc.gov.in.; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India. rchecker@barc.gov.in. |
| Source: | Cell communication and signaling : CCS [Cell Commun Signal] 2025 Sep 03; Vol. 23 (1), pp. 393. Date of Electronic Publication: 2025 Sep 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40903791 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Targeting mitochondrial proteases CLPP and LONP1 via disruption of mitochondrial redox homeostasis induces proteotoxic stress and suppresses tumor progression. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Nandha+SR%22">Nandha SR</searchLink>; Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India.<br /><searchLink fieldCode="AU" term="%22Patwardhan+RS%22">Patwardhan RS</searchLink>; Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India.<br /><searchLink fieldCode="AU" term="%22Sharma+D%22">Sharma D</searchLink>; Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India.<br /><searchLink fieldCode="AU" term="%22Sandur+SK%22">Sandur SK</searchLink>; Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India. sskumar@barc.gov.in.; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India. sskumar@barc.gov.in.<br /><searchLink fieldCode="AU" term="%22Checker+R%22">Checker R</searchLink>; Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India. rchecker@barc.gov.in.; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India. rchecker@barc.gov.in. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101170464%22">Cell communication and signaling : CCS</searchLink> [Cell Commun Signal] 2025 Sep 03; Vol. 23 (1), pp. 393. <i>Date of Electronic Publication: </i>2025 Sep 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101170464 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1478-811X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221478811X%22">1478811X </searchLink><i>NLM ISO Abbreviation: </i>Cell Commun Signal <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40903791 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s12964-025-02127-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 393 Titles: – TitleFull: Targeting mitochondrial proteases CLPP and LONP1 via disruption of mitochondrial redox homeostasis induces proteotoxic stress and suppresses tumor progression. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Nandha SR – PersonEntity: Name: NameFull: Patwardhan RS – PersonEntity: Name: NameFull: Sharma D – PersonEntity: Name: NameFull: Sandur SK – PersonEntity: Name: NameFull: Checker R IsPartOfRelationships: – BibEntity: Dates: – D: 03 M: 09 Text: 2025 Sep 03 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1478-811X Numbering: – Type: volume Value: 23 – Type: issue Value: 1 Titles: – TitleFull: Cell communication and signaling : CCS Type: main |
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