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Spirometry thresholds for clinical trial eligibility: time for urgent re-evaluation.

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Title: Spirometry thresholds for clinical trial eligibility: time for urgent re-evaluation.
Authors: Bokobza I; National Heart and Lung Institute, Imperial College London, London, UK.; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK., Le Sayec M; Clinical Trials Accelerator Platform, London, UK.; King's College Hospital NHS Foundation Trust, London, UK., Bossley C; Clinical Trials Accelerator Platform, London, UK.; King's College Hospital NHS Foundation Trust, London, UK., Brugha R; Clinical Trials Accelerator Platform, London, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Davies JC; National Heart and Lung Institute, Imperial College London, London, UK.; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK., Dawson C; Clinical Trials Accelerator Platform, London, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Holt L; Clinical Trials Accelerator Platform, London, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Hughes DA; National Heart and Lung Institute, Imperial College London, London, UK.; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK., Needham Y; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK., Pao C; Clinical Trials Accelerator Platform, London, UK.; Barts Health NHS Trust, London, UK., Ruiz G; Clinical Trials Accelerator Platform, London, UK.; King's College Hospital NHS Foundation Trust, London, UK., Safavi S; Clinical Trials Accelerator Platform, London, UK.; Barts Health NHS Trust, London, UK., Saunders C; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK., Shafi N; Clinical Trials Accelerator Platform, London, UK.; Barts Health NHS Trust, London, UK., Simmonds NJ; National Heart and Lung Institute, Imperial College London, London, UK.; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK., Waller MD; Clinical Trials Accelerator Platform, London, UK.; King's College Hospital NHS Foundation Trust, London, UK.; King's College London, London, UK., Watson D; Clinical Trials Accelerator Platform, London, UK.; Barts Health NHS Trust, London, UK., Davies G; Clinical Trials Accelerator Platform, London, UK gwyneth.davies@ucl.ac.uk.; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Source: Thorax [Thorax] 2025 Oct 15; Vol. 80 (11), pp. 849-852. Date of Electronic Publication: 2025 Oct 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 0417353 Publication Model: Electronic Cited Medium: Internet ISSN: 1468-3296 (Electronic) Linking ISSN: 00406376 NLM ISO Abbreviation: Thorax Subsets: MEDLINE
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  Data: Spirometry thresholds for clinical trial eligibility: time for urgent re-evaluation.
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  Data: <searchLink fieldCode="AU" term="%22Bokobza+I%22">Bokobza I</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Le+Sayec+M%22">Le Sayec M</searchLink>; Clinical Trials Accelerator Platform, London, UK.; King's College Hospital NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Bossley+C%22">Bossley C</searchLink>; Clinical Trials Accelerator Platform, London, UK.; King's College Hospital NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Brugha+R%22">Brugha R</searchLink>; Clinical Trials Accelerator Platform, London, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Davies+JC%22">Davies JC</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Dawson+C%22">Dawson C</searchLink>; Clinical Trials Accelerator Platform, London, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Holt+L%22">Holt L</searchLink>; Clinical Trials Accelerator Platform, London, UK.; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Hughes+DA%22">Hughes DA</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Needham+Y%22">Needham Y</searchLink>; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Pao+C%22">Pao C</searchLink>; Clinical Trials Accelerator Platform, London, UK.; Barts Health NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Ruiz+G%22">Ruiz G</searchLink>; Clinical Trials Accelerator Platform, London, UK.; King's College Hospital NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Safavi+S%22">Safavi S</searchLink>; Clinical Trials Accelerator Platform, London, UK.; Barts Health NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Saunders+C%22">Saunders C</searchLink>; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Shafi+N%22">Shafi N</searchLink>; Clinical Trials Accelerator Platform, London, UK.; Barts Health NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Simmonds+NJ%22">Simmonds NJ</searchLink>; National Heart and Lung Institute, Imperial College London, London, UK.; Clinical Trials Accelerator Platform, London, UK.; Royal Brompton & Harefield NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Waller+MD%22">Waller MD</searchLink>; Clinical Trials Accelerator Platform, London, UK.; King's College Hospital NHS Foundation Trust, London, UK.; King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Watson+D%22">Watson D</searchLink>; Clinical Trials Accelerator Platform, London, UK.; Barts Health NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Davies+G%22">Davies G</searchLink>; Clinical Trials Accelerator Platform, London, UK gwyneth.davies@ucl.ac.uk.; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
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