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Early-preschool wheeze trajectories are predominantly nonallergic with distinct biologic and microbiome traits.

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Title: Early-preschool wheeze trajectories are predominantly nonallergic with distinct biologic and microbiome traits.
Authors: Lu Z; Department of Public Health Sciences, Queen's University, Kingston, Ontario, Canada; Department of Mathematics and Statistics, Queen's University, Kingston, Ontario, Canada., Petersen C; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Dai R; Department of Pediatrics, and Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada., Reyna ME; Department of Pediatrics, and Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada., Ahmadiankalati M; Department of Public Health Sciences, Queen's University, Kingston, Ontario, Canada., Sifuentes E; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Dai DLY; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Hoskinson C; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Del Bel KL; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Miliku K; Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Moraes TJ; Department of Pediatrics, and Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada., Mandhane PJ; Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada; Faculty of Medicine & Health Sciences, UCSI University, Kuala Lumpur, Malaysia., Becker AB; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada; Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada., Azad MB; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada; Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada., Simons E; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada; Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada; Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Lou W; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada., Ambalavanan A; Department of Biomedical and Molecular Science, Queen's University, Kingston, Ontario, Canada., Duan Q; Department of Biomedical and Molecular Science, Queen's University, Kingston, Ontario, Canada., Turvey SE; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Subbarao P; Department of Pediatrics, and Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: Padmaja.subbarao@sickkids.ca.
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2025 Dec; Vol. 156 (6), pp. 1556-1572. Date of Electronic Publication: 2025 Sep 03.
Publication Type: Journal Article
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Early-preschool wheeze trajectories are predominantly nonallergic with distinct biologic and microbiome traits.
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  Data: <searchLink fieldCode="AU" term="%22Lu+Z%22">Lu Z</searchLink>; Department of Public Health Sciences, Queen's University, Kingston, Ontario, Canada; Department of Mathematics and Statistics, Queen's University, Kingston, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Petersen+C%22">Petersen C</searchLink>; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Dai+R%22">Dai R</searchLink>; Department of Pediatrics, and Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Reyna+ME%22">Reyna ME</searchLink>; Department of Pediatrics, and Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ahmadiankalati+M%22">Ahmadiankalati M</searchLink>; Department of Public Health Sciences, Queen's University, Kingston, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Sifuentes+E%22">Sifuentes E</searchLink>; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Dai+DLY%22">Dai DLY</searchLink>; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Hoskinson+C%22">Hoskinson C</searchLink>; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Del+Bel+KL%22">Del Bel KL</searchLink>; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Miliku+K%22">Miliku K</searchLink>; Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Moraes+TJ%22">Moraes TJ</searchLink>; Department of Pediatrics, and Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Mandhane+PJ%22">Mandhane PJ</searchLink>; Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada; Faculty of Medicine & Health Sciences, UCSI University, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Becker+AB%22">Becker AB</searchLink>; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada; Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.<br /><searchLink fieldCode="AU" term="%22Azad+MB%22">Azad MB</searchLink>; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada; Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.<br /><searchLink fieldCode="AU" term="%22Simons+E%22">Simons E</searchLink>; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada; Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada; Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.<br /><searchLink fieldCode="AU" term="%22Lou+W%22">Lou W</searchLink>; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ambalavanan+A%22">Ambalavanan A</searchLink>; Department of Biomedical and Molecular Science, Queen's University, Kingston, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Duan+Q%22">Duan Q</searchLink>; Department of Biomedical and Molecular Science, Queen's University, Kingston, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Turvey+SE%22">Turvey SE</searchLink>; Department of Pediatrics, Child and Family Research Institute, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Subbarao+P%22">Subbarao P</searchLink>; Department of Pediatrics, and Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: Padmaja.subbarao@sickkids.ca.
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  Data: <searchLink fieldCode="JN" term="%221275002%22">The Journal of allergy and clinical immunology</searchLink> [J Allergy Clin Immunol] 2025 Dec; Vol. 156 (6), pp. 1556-1572. <i>Date of Electronic Publication: </i>2025 Sep 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1275002 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6825 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200916749%22">00916749 </searchLink><i>NLM ISO Abbreviation: </i>J Allergy Clin Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jaci.2025.07.034
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              Text: 2025 Dec
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