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Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth.

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Title: Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth.
Authors: Cheng A; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Lichenstein S; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Chaarani B; Department of Psychiatry, University of Vermont, Burlington, VT, USA., Liang Q; Department of Biomedical Engineering, Yale University, New Haven, CT, USA., Babaeianjelodar M; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Riley SJ; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Luo W; Department of Biomedical Engineering, Yale University, New Haven, CT, USA., Horien C; Interdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA.; MD/PhD program, Yale School of Medicine, New Haven, CT, USA., Greene AS; Interdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA.; MD/PhD program, Yale School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, USA., Banaschewski T; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Center for Mental Health (DZPG), partner site Mannheim-Heidelberg-Ulm, Mannheim, Germany., Bokde ALW; Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland., Desrivières S; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Flor H; Institute of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Department of Psychology, School of Social Sciences, University of Mannheim, Mannheim, Germany., Grigis A; NeuroSpin, CEA, Université Paris-Saclay, Gif-sur-Yvette, France., Gowland P; Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK., Heinz A; Department of Psychiatry and Psychotherapy CCM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Brühl R; Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany., Martinot JL; Institut National de la Santé et de la Recherche Médicale, INSERM U 1299 'Trajectoires développementales en psychiatrie', Université Paris-Saclay, Ecole Normale supérieure Paris-Saclay, CNRS, Centre Borelli, Gif-sur-Yvette, France., Martinot MP; Institut National de la Santé et de la Recherche Médicale, INSERM U 1299 'Trajectoires développementales en psychiatrie', Université Paris-Saclay, Ecole Normale supérieure Paris-Saclay, CNRS, Centre Borelli, Gif-sur-Yvette, France.; AP-HP. Sorbonne Université, Department of Child and Adolescent Psychiatry, Pitié-Salpêtrière Hospital, Paris, France., Artiges E; Institut National de la Santé et de la Recherche Médicale, INSERM U 1299 'Trajectoires développementales en psychiatrie', Université Paris-Saclay, Ecole Normale supérieure Paris-Saclay, CNRS, Centre Borelli, Gif-sur-Yvette, France.; Psychiatry Department, EPS Barthélémy Durand, Etampes, France., Nees F; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Institute of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Institute of Medical Psychology and Medical Sociology, University Medical Center Schleswig-Holstein, Kiel University, Kiel, Germany., Papadopoulos Orfanos D; NeuroSpin, CEA, Université Paris-Saclay, Gif-sur-Yvette, France., Poustka L; Department of Child and Adolescent Psychiatry, Center for Psychosocial Medicine, University Hospital Heidelberg, Heidelberg, Germany., Hohmann S; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Holz N; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Baeuchl C; Department of Psychiatry and Psychotherapy, Technische Universität Dresden, Dresden, Germany., Smolka MN; Department of Psychiatry and Psychotherapy, Technische Universität Dresden, Dresden, Germany., Vaidya N; Centre for Population Neuroscience and Stratified Medicine (PONS), Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Germany., Walter H; Department of Psychiatry and Psychotherapy CCM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Whelan R; School of Psychology and Global Brain Health Institute, Trinity College Dublin, Dublin, Ireland., Schumann G; Centre for Population Neuroscience and Stratified Medicine (PONS), Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Germany.; Centre for Population Neuroscience and Precision Medicine (PONS), Institute for Science and Technology of Brain-inspired Intelligence (ISTBI), Fudan University, Shanghai, China., Constable RT; Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA., Pearlson G; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA., Garavan H; Department of Psychiatry, University of Vermont, Burlington, VT, USA.; Department of Psychology, University of Vermont, Burlington, VT, USA., Yip SW; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA. sarah.yip@yale.edu.; Child Study Center, Yale School of Medicine, New Haven, CT, USA. sarah.yip@yale.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Feb; Vol. 31 (2), pp. 953-962. Date of Electronic Publication: 2025 Sep 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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