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Patient-Specific Regulatory Network Rewiring in Inflammatory Bowel Disease: How Genetic Polymorphisms Divert Incoming Signals and Contribute to Disease Pathogenesis.

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Bibliographic Details
Title: Patient-Specific Regulatory Network Rewiring in Inflammatory Bowel Disease: How Genetic Polymorphisms Divert Incoming Signals and Contribute to Disease Pathogenesis.
Authors: Bohar B; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom., Thomas JP; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.; UKRI MRC Laboratory of Medical Sciences, Hammersmith Hospital Campus, London, United Kingdom., Liu Y; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom., Brooks-Warburton J; Gut Microbes and Health Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich, United Kingdom.; Department of Clinical, Pharmaceutical and Biological Sciences, University of Hertfordshire, Hertford, United Kingdom.; Department of Gastroenterology, Lister Hospital, Stevenage, United Kingdom., Verstockt B; Department Gastroenterology & Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.; Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Powell N; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom., Korcsmaros T; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.; Gut Microbes and Health Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich, United Kingdom.; NIHR Imperial BRC Organoid Facility, Imperial College London, London, United Kingdom., Modos D; Gut Microbes and Health Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich, United Kingdom.; Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Source: Inflammatory bowel diseases [Inflamm Bowel Dis] 2025 Oct 01; Vol. 31 (10), pp. 2665-2680.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9508162 Publication Model: Print Cited Medium: Internet ISSN: 1536-4844 (Electronic) Linking ISSN: 10780998 NLM ISO Abbreviation: Inflamm Bowel Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1536-4844
DOI:10.1093/ibd/izaf173