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Published Population Pharmacokinetic Models of Imatinib Perform Poorly on TDM Data from Pediatric Patients.

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Title: Published Population Pharmacokinetic Models of Imatinib Perform Poorly on TDM Data from Pediatric Patients.
Authors: Yang T; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Rasmussen ASB; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Weimann A; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Thastrup M; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Rank CU; Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Als-Nielsen B; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Malmros J; Childhood Cancer Unit, Karolinska University Hospital, and Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Wik HS; Department of Haematology, Oslo University Hospital Rikshospitalet, Oslo, Norway., Lohi O; TamCAM Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Centre, Tampere University Hospital, Tampere, Finland., Overgaard U; Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Johannsdottir IMR; Department of Pediatric Hematology and Oncology, Rikshospitalet, Oslo University Hospital, Oslo, Norway., Vaitkeviciene G; Center for Pediatric Oncology and Hematology, Clinics for Children Diseases, Vilnius University, Vilnius, Lithuania., Dalhoff K; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark., Schmiegelow K; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark., Lund TM; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. trine.lund@sund.ku.dk.; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark. trine.lund@sund.ku.dk.
Source: Targeted oncology [Target Oncol] 2025 Sep; Vol. 20 (5), pp. 871-886. Date of Electronic Publication: 2025 Sep 08.
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Springer-Verlag France Country of Publication: France NLM ID: 101270595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1776-260X (Electronic) Linking ISSN: 17762596 NLM ISO Abbreviation: Target Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Published Population Pharmacokinetic Models of Imatinib Perform Poorly on TDM Data from Pediatric Patients.
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  Data: <searchLink fieldCode="AU" term="%22Yang+T%22">Yang T</searchLink>; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Rasmussen+ASB%22">Rasmussen ASB</searchLink>; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Weimann+A%22">Weimann A</searchLink>; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Thastrup+M%22">Thastrup M</searchLink>; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Rank+CU%22">Rank CU</searchLink>; Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Als-Nielsen+B%22">Als-Nielsen B</searchLink>; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Malmros+J%22">Malmros J</searchLink>; Childhood Cancer Unit, Karolinska University Hospital, and Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Wik+HS%22">Wik HS</searchLink>; Department of Haematology, Oslo University Hospital Rikshospitalet, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Lohi+O%22">Lohi O</searchLink>; TamCAM Center, Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Centre, Tampere University Hospital, Tampere, Finland.<br /><searchLink fieldCode="AU" term="%22Overgaard+U%22">Overgaard U</searchLink>; Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Johannsdottir+IMR%22">Johannsdottir IMR</searchLink>; Department of Pediatric Hematology and Oncology, Rikshospitalet, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Vaitkeviciene+G%22">Vaitkeviciene G</searchLink>; Center for Pediatric Oncology and Hematology, Clinics for Children Diseases, Vilnius University, Vilnius, Lithuania.<br /><searchLink fieldCode="AU" term="%22Dalhoff+K%22">Dalhoff K</searchLink>; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Schmiegelow+K%22">Schmiegelow K</searchLink>; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lund+TM%22">Lund TM</searchLink>; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. trine.lund@sund.ku.dk.; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark. trine.lund@sund.ku.dk.
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  Data: <searchLink fieldCode="JN" term="%22101270595%22">Targeted oncology</searchLink> [Target Oncol] 2025 Sep; Vol. 20 (5), pp. 871-886. <i>Date of Electronic Publication: </i>2025 Sep 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+France%22">Springer-Verlag France </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>101270595 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1776-260X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217762596%22">17762596 </searchLink><i>NLM ISO Abbreviation: </i>Target Oncol <i>Subsets: </i>MEDLINE
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              Text: 2025 Sep
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