Deletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice.
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| Title: | Deletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice. |
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| Authors: | Huber LS; Institute of Pharmacology and Toxicology, Goethe University Frankfurt, Frankfurt, Germany., Merline R; Institute of Pharmacology and Toxicology, Goethe University Frankfurt, Frankfurt, Germany., Zeng-Brouwers J; Institute of Pharmacology and Toxicology, Goethe University Frankfurt, Frankfurt, Germany., Vutukuri R; Institute of Pharmacology and Toxicology, Goethe University Frankfurt, Frankfurt, Germany., Kraus N; Medical Clinic 1, Goethe University Frankfurt, University Hospital, Frankfurt, Germany., Ortiz C; Medical Clinic 1, Goethe University Frankfurt, University Hospital, Frankfurt, Germany., Guenther S; Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany., Buhl EM; Electron Microscopic Facility, RWTH Aachen University Hospital, Aachen, Germany., Hahnefeld L; Institute of Clinical Pharmacology, University Hospital Frankfurt, Frankfurt, Germany., Gurke R; Institute of Clinical Pharmacology, University Hospital Frankfurt, Frankfurt, Germany., Bein J; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt, Germany., Karimova M; Dr. Senckenberg Institute of Pathology, University Hospital, Frankfurt, Germany., Wurzel P; Institute of Pharmacology and Toxicology, Goethe University Frankfurt, Frankfurt, Germany., Boor P; Electron Microscopic Facility, RWTH Aachen University Hospital, Aachen, Germany.; Georg Speyer Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany., Welsch C; Medical Clinic 1, Goethe University Frankfurt, University Hospital, Frankfurt, Germany., Wild P; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt, Germany., Pfeilschifter J; Institute of Pharmacology and Toxicology, Goethe University Frankfurt, Frankfurt, Germany., Kögel D; Institute of Pathology, RWTH Aachen University, Aachen, Germany., Wygrecka M; Experimental Neurosurgery, University Hospital Frankfurt, Frankfurt, Germany.; Center for Infection and Genomics of the Lung (CIGL), Universities of Giessen and Marburg Lung Center, Giessen, Germany., Trebicka J; Institute of Lung Health, Giessen, Germany.; Department of Internal Medicine B, University Hospital Münster, Münster, Germany., Bartoszewski R; European Foundation for Study of Chronic Liver Failure, EF-Clif, Barcelona, Spain., Dikic I; Department of Biophysics, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland., Schaefer L; Institute of Pharmacology and Toxicology, Goethe University Frankfurt, Frankfurt, Germany. |
| Source: | American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2025 Nov 01; Vol. 329 (5), pp. C1360-C1379. Date of Electronic Publication: 2025 Sep 08. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1522-1563 |
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| DOI: | 10.1152/ajpcell.00544.2025 |
