Structure-guided loop grafting improves expression and stability of influenza neuraminidase for vaccine development.
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| Title: | Structure-guided loop grafting improves expression and stability of influenza neuraminidase for vaccine development. |
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| Authors: | Rijal P; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom., Wei L; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom., Paesen GC; Division of Structural Biology, Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Stuart DI; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Division of Structural Biology, Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Haworth M; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom., Huang KA; Graduate Institute of Immunology and Department of Paediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.; Genomics Research Center, Academia Sinica, Taipei, Taiwan., Bowden TA; Division of Structural Biology, Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Townsend ARM; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom. |
| Source: | ELife [Elife] 2025 Sep 09; Vol. 14. Date of Electronic Publication: 2025 Sep 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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