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Identification of proteins in semen-derived extracellular vesicles that bind to Tat and NF-κB and that may impair HIV replication.

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Title: Identification of proteins in semen-derived extracellular vesicles that bind to Tat and NF-κB and that may impair HIV replication.
Authors: Okeoma BC; Department of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, USA., Kaddour H; Department of Pharmacology, Stony Brook University Renaissance School of Medicine, Stony Brook, NY 11794-8651, USA., Naushad W; Department of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, USA., Paromov V; Meharry Medical College, Meharry Proteomics Core, RCMI Research Capacity Core, School of Medicine, Nashville, TN 37208, USA., Chaudhary A; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242-1109, USA.; Medical Service, Iowa City Veterans Affairs Medical Center, University of Iowa, 604 Highway 6, Iowa City, IA 52246-2208, USA., Noghero A; Lovelace Biomedical Institute, Albuquerque, NM 87108-5127, USA., Stapleton JT; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242-1109, USA.; Medical Service, Iowa City Veterans Affairs Medical Center, University of Iowa, 604 Highway 6, Iowa City, IA 52246-2208, USA., Okeoma CM; Department of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, USA.; Department of Pharmacology, Stony Brook University Renaissance School of Medicine, Stony Brook, NY 11794-8651, USA.; Lovelace Biomedical Institute, Albuquerque, NM 87108-5127, USA.
Source: Science signaling [Sci Signal] 2025 Sep 09; Vol. 18 (903), pp. eado9243. Date of Electronic Publication: 2025 Sep 09.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1937-9145
DOI:10.1126/scisignal.ado9243