Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development.

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Title: Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development.
Authors: Pierson JB; Health and Environmental Sciences Institute, Washington, DC, USA., Bahinski A; Vivodyne, Philadelphia, PA, USA., Berridge B; B2 Pathology Solutions, Raleigh-Durham, NC, USA., Bramham D; LabCorp Drug Development, Harrogate, UK., Bourcier T; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Chaudhary KW; Bristol Myers Squibb, Lawrenceville, NJ, USA., Eldridge S; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick, MD, USA., Kanda Y; National Institute of Health Sciences Japan, Kawasaki City, Japan., Mattes WB; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA., Oliphant J; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA., Pang L; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA., Savtchenko A; Nanotools Bioscience, San Diego, CA, USA., Siegel J; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Simpson N; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Tu C; Stanford University School of Medicine, Stanford Cardiovascular Institute, Stanford, CA, USA., Wange R; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Wu JC; Stanford University School of Medicine, Stanford Cardiovascular Institute, Stanford, CA, USA.; Greenstone Biosciences, Palo Alto, CA, USA., Yang X; RTI International, Washington, DC, USA.
Source: International journal of toxicology [Int J Toxicol] 2025 Nov-Dec; Vol. 44 (6), pp. 499-506. Date of Electronic Publication: 2025 Sep 09.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1092-874X (Electronic) Linking ISSN: 10915818 NLM ISO Abbreviation: Int J Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1092-874X
DOI:10.1177/10915818251375348