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Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development.

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Title: Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development.
Authors: Pierson JB; Health and Environmental Sciences Institute, Washington, DC, USA., Bahinski A; Vivodyne, Philadelphia, PA, USA., Berridge B; B2 Pathology Solutions, Raleigh-Durham, NC, USA., Bramham D; LabCorp Drug Development, Harrogate, UK., Bourcier T; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Chaudhary KW; Bristol Myers Squibb, Lawrenceville, NJ, USA., Eldridge S; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick, MD, USA., Kanda Y; National Institute of Health Sciences Japan, Kawasaki City, Japan., Mattes WB; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA., Oliphant J; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA., Pang L; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA., Savtchenko A; Nanotools Bioscience, San Diego, CA, USA., Siegel J; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Simpson N; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Tu C; Stanford University School of Medicine, Stanford Cardiovascular Institute, Stanford, CA, USA., Wange R; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Wu JC; Stanford University School of Medicine, Stanford Cardiovascular Institute, Stanford, CA, USA.; Greenstone Biosciences, Palo Alto, CA, USA., Yang X; RTI International, Washington, DC, USA.
Source: International journal of toxicology [Int J Toxicol] 2025 Nov-Dec; Vol. 44 (6), pp. 499-506. Date of Electronic Publication: 2025 Sep 09.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1092-874X (Electronic) Linking ISSN: 10915818 NLM ISO Abbreviation: Int J Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development.
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  Data: <searchLink fieldCode="AU" term="%22Pierson+JB%22">Pierson JB</searchLink>; Health and Environmental Sciences Institute, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Bahinski+A%22">Bahinski A</searchLink>; Vivodyne, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Berridge+B%22">Berridge B</searchLink>; B2 Pathology Solutions, Raleigh-Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Bramham+D%22">Bramham D</searchLink>; LabCorp Drug Development, Harrogate, UK.<br /><searchLink fieldCode="AU" term="%22Bourcier+T%22">Bourcier T</searchLink>; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chaudhary+KW%22">Chaudhary KW</searchLink>; Bristol Myers Squibb, Lawrenceville, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Eldridge+S%22">Eldridge S</searchLink>; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kanda+Y%22">Kanda Y</searchLink>; National Institute of Health Sciences Japan, Kawasaki City, Japan.<br /><searchLink fieldCode="AU" term="%22Mattes+WB%22">Mattes WB</searchLink>; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Oliphant+J%22">Oliphant J</searchLink>; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Pang+L%22">Pang L</searchLink>; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Savtchenko+A%22">Savtchenko A</searchLink>; Nanotools Bioscience, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Siegel+J%22">Siegel J</searchLink>; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22Simpson+N%22">Simpson N</searchLink>; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22Tu+C%22">Tu C</searchLink>; Stanford University School of Medicine, Stanford Cardiovascular Institute, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wange+R%22">Wange R</searchLink>; Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wu+JC%22">Wu JC</searchLink>; Stanford University School of Medicine, Stanford Cardiovascular Institute, Stanford, CA, USA.; Greenstone Biosciences, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; RTI International, Washington, DC, USA.
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  Data: <searchLink fieldCode="JN" term="%229708436%22">International journal of toxicology</searchLink> [Int J Toxicol] 2025 Nov-Dec; Vol. 44 (6), pp. 499-506. <i>Date of Electronic Publication: </i>2025 Sep 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Sage+Publications%22">Sage Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9708436 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1092-874X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210915818%22">10915818 </searchLink><i>NLM ISO Abbreviation: </i>Int J Toxicol <i>Subsets: </i>MEDLINE
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              Text: 2025 Nov-Dec
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