Identification of p38 MAPK inhibition as a neuroprotective strategy for combinatorial SMA therapy.
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| Title: | Identification of p38 MAPK inhibition as a neuroprotective strategy for combinatorial SMA therapy. |
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| Authors: | Carlini MJ; Department of Neurology, Columbia University, New York, NY, 10032, USA., Espinoza-Derout J; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Van Alstyne M; Department of Neurology, Columbia University, New York, NY, 10032, USA.; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Tisdale S; Department of Neurology, Columbia University, New York, NY, 10032, USA.; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Workman E; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Triplett MK; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Tattoli I; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Yadav S; Department of Neurology, Columbia University, New York, NY, 10032, USA., Henderson CE; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY, 10032, USA., Watterson DM; Department of Pharmacology, Northwestern University, Chicago, IL, 60611, USA., Pellizzoni L; Department of Neurology, Columbia University, New York, NY, 10032, USA. lp2284@cumc.columbia.edu.; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA. lp2284@cumc.columbia.edu.; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY, 10032, USA. lp2284@cumc.columbia.edu. |
| Source: | EMBO molecular medicine [EMBO Mol Med] 2025 Oct; Vol. 17 (10), pp. 2762-2786. Date of Electronic Publication: 2025 Sep 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1757-4684 |
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| DOI: | 10.1038/s44321-025-00303-6 |
