Identification of p38 MAPK inhibition as a neuroprotective strategy for combinatorial SMA therapy.

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Title: Identification of p38 MAPK inhibition as a neuroprotective strategy for combinatorial SMA therapy.
Authors: Carlini MJ; Department of Neurology, Columbia University, New York, NY, 10032, USA., Espinoza-Derout J; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Van Alstyne M; Department of Neurology, Columbia University, New York, NY, 10032, USA.; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Tisdale S; Department of Neurology, Columbia University, New York, NY, 10032, USA.; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Workman E; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Triplett MK; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Tattoli I; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Yadav S; Department of Neurology, Columbia University, New York, NY, 10032, USA., Henderson CE; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY, 10032, USA., Watterson DM; Department of Pharmacology, Northwestern University, Chicago, IL, 60611, USA., Pellizzoni L; Department of Neurology, Columbia University, New York, NY, 10032, USA. lp2284@cumc.columbia.edu.; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA. lp2284@cumc.columbia.edu.; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY, 10032, USA. lp2284@cumc.columbia.edu.
Source: EMBO molecular medicine [EMBO Mol Med] 2025 Oct; Vol. 17 (10), pp. 2762-2786. Date of Electronic Publication: 2025 Sep 08.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
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  Data: Identification of p38 MAPK inhibition as a neuroprotective strategy for combinatorial SMA therapy.
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  Data: <searchLink fieldCode="AU" term="%22Carlini+MJ%22">Carlini MJ</searchLink>; Department of Neurology, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Espinoza-Derout+J%22">Espinoza-Derout J</searchLink>; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Van+Alstyne+M%22">Van Alstyne M</searchLink>; Department of Neurology, Columbia University, New York, NY, 10032, USA.; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Tisdale+S%22">Tisdale S</searchLink>; Department of Neurology, Columbia University, New York, NY, 10032, USA.; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Workman+E%22">Workman E</searchLink>; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Triplett+MK%22">Triplett MK</searchLink>; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Tattoli+I%22">Tattoli I</searchLink>; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Yadav+S%22">Yadav S</searchLink>; Department of Neurology, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Henderson+CE%22">Henderson CE</searchLink>; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Watterson+DM%22">Watterson DM</searchLink>; Department of Pharmacology, Northwestern University, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Pellizzoni+L%22">Pellizzoni L</searchLink>; Department of Neurology, Columbia University, New York, NY, 10032, USA. lp2284@cumc.columbia.edu.; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA. lp2284@cumc.columbia.edu.; Center for Motor Neuron Biology and Disease, Columbia University, New York, NY, 10032, USA. lp2284@cumc.columbia.edu.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2025 Oct; Vol. 17 (10), pp. 2762-2786. <i>Date of Electronic Publication: </i>2025 Sep 08.
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