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Genetic variance in the murine defensin locus modulates glucose homeostasis.

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Title: Genetic variance in the murine defensin locus modulates glucose homeostasis.
Authors: Masson SWC; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia. stewart.masson@sydney.edu.au.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia. stewart.masson@sydney.edu.au., Simpson RC; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.; Melanoma Institute Australia, Sydney, NSW, Australia.; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Cutler HB; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., Carlos PW; School of Chemistry, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, Sydney, NSW, Australia., Marian OC; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Yau B; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Potter M; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., Madsen S; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., Cooke KC; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., Craw NR; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., Fuller OK; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., Harney DJ; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., Larance M; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Cooney GJ; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., Morahan G; Centre for Diabetes Research, Harry Perkins Institute of Medical Research, Murdoch, WA, Australia., Shanahan ER; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., Kebede MA; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Hodgkins C; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., Payne RJ; School of Chemistry, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, Sydney, NSW, Australia., Stöckli J; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia., James DE; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia. david.james@sydney.edu.au.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia. david.james@sydney.edu.au.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia. david.james@sydney.edu.au.
Source: The EMBO journal [EMBO J] 2025 Oct; Vol. 44 (20), pp. 5694-5711. Date of Electronic Publication: 2025 Sep 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
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  Data: Genetic variance in the murine defensin locus modulates glucose homeostasis.
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  Data: <searchLink fieldCode="AU" term="%22Masson+SWC%22">Masson SWC</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia. stewart.masson@sydney.edu.au.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia. stewart.masson@sydney.edu.au.<br /><searchLink fieldCode="AU" term="%22Simpson+RC%22">Simpson RC</searchLink>; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.; Melanoma Institute Australia, Sydney, NSW, Australia.; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Cutler+HB%22">Cutler HB</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Carlos+PW%22">Carlos PW</searchLink>; School of Chemistry, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Marian+OC%22">Marian OC</searchLink>; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Yau+B%22">Yau B</searchLink>; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Potter+M%22">Potter M</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Madsen+S%22">Madsen S</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Cooke+KC%22">Cooke KC</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Craw+NR%22">Craw NR</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Fuller+OK%22">Fuller OK</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Harney+DJ%22">Harney DJ</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Larance+M%22">Larance M</searchLink>; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Cooney+GJ%22">Cooney GJ</searchLink>; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Morahan+G%22">Morahan G</searchLink>; Centre for Diabetes Research, Harry Perkins Institute of Medical Research, Murdoch, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Shanahan+ER%22">Shanahan ER</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Kebede+MA%22">Kebede MA</searchLink>; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Hodgkins+C%22">Hodgkins C</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Payne+RJ%22">Payne RJ</searchLink>; School of Chemistry, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Stöckli+J%22">Stöckli J</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22James+DE%22">James DE</searchLink>; School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia. david.james@sydney.edu.au.; Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia. david.james@sydney.edu.au.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia. david.james@sydney.edu.au.
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