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Results of TOR001: An open-label single patient study using targeted bacteriophage therapy for the treatment of chronic urinary tract infection.

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Title: Results of TOR001: An open-label single patient study using targeted bacteriophage therapy for the treatment of chronic urinary tract infection.
Authors: Cook JD; Unity Health Toronto, St. Joseph's Health Centre, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Hooey PB; Unity Health Toronto, St. Joseph's Health Centre, Toronto, Ontario, Canada., Salazar KC; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA., Clark JR; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA., Jain U; Unity Health Toronto, St. Joseph's Health Centre, Toronto, Ontario, Canada., Fernando C; Unity Health Toronto, St. Joseph's Health Centre, Toronto, Ontario, Canada., Harvey H; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada., Cervantes A; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA., Omagari S; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA., Blankstein U; Department of Surgery, McMaster University, Hamilton, Ontario, Canada., Kropinski AM; Department of Pathobiology, University of Guelph, Ontario, Canada., Davidson AR; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada., Maxwell KL; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada., Burrows LL; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada., Terwilliger AL; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA., Maresso AW; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA., German GJ; Unity Health Toronto, St. Joseph's Health Centre, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Unity Health Toronto, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada. Electronic address: Gregory.German@unityhealth.to.
Source: International journal of antimicrobial agents [Int J Antimicrob Agents] 2025 Dec; Vol. 66 (6), pp. 107613. Date of Electronic Publication: 2025 Sep 08.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7913 (Electronic) Linking ISSN: 09248579 NLM ISO Abbreviation: Int J Antimicrob Agents Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Results of TOR001: An open-label single patient study using targeted bacteriophage therapy for the treatment of chronic urinary tract infection.
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  Data: <searchLink fieldCode="AU" term="%22Cook+JD%22">Cook JD</searchLink>; Unity Health Toronto, St. Joseph's Health Centre, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Hooey+PB%22">Hooey PB</searchLink>; Unity Health Toronto, St. Joseph's Health Centre, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Salazar+KC%22">Salazar KC</searchLink>; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Clark+JR%22">Clark JR</searchLink>; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Jain+U%22">Jain U</searchLink>; Unity Health Toronto, St. Joseph's Health Centre, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Fernando+C%22">Fernando C</searchLink>; Unity Health Toronto, St. Joseph's Health Centre, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Harvey+H%22">Harvey H</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Cervantes+A%22">Cervantes A</searchLink>; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Omagari+S%22">Omagari S</searchLink>; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Blankstein+U%22">Blankstein U</searchLink>; Department of Surgery, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Kropinski+AM%22">Kropinski AM</searchLink>; Department of Pathobiology, University of Guelph, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Davidson+AR%22">Davidson AR</searchLink>; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Maxwell+KL%22">Maxwell KL</searchLink>; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Burrows+LL%22">Burrows LL</searchLink>; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Terwilliger+AL%22">Terwilliger AL</searchLink>; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Maresso+AW%22">Maresso AW</searchLink>; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research (TAILΦR), Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22German+GJ%22">German GJ</searchLink>; Unity Health Toronto, St. Joseph's Health Centre, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Unity Health Toronto, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada. Electronic address: Gregory.German@unityhealth.to.
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  Data: <searchLink fieldCode="JN" term="%229111860%22">International journal of antimicrobial agents</searchLink> [Int J Antimicrob Agents] 2025 Dec; Vol. 66 (6), pp. 107613. <i>Date of Electronic Publication: </i>2025 Sep 08.
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